Negative?results in Structural Biology

Negative results in structural biology is a term used to refer to results obtained when a structure is not found even after trying to identify it. Negative results can also refer to studies which fail to validate a hypothesis or identify a structure. Negative results are an important part of any structural biology study and provide insight into a structure’s limitations, helping to inform future research. In addition, they often provide critical evidence to inform and shape the development of models and of structural databases like the Protein Data Bank. Negative results can also introduce new ideas, alternative methods, and novel applications which lead to new scientific advancements.