Research Topic · Peer-Reviewed

Hyperlipidemia

Hyperlipidemia is a metabolic condition characterized by elevated concentrations of lipids in the blood, including cholesterol carried in low-density lipoprotein, triglycerides, or both, often accompanied by reduced high-density lipoprotein. It arises from primary (genetic) causes such as familial combined hyperlipi…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 80× across the literature 🔖 ISSN 2835-513X 🗓 Reviewed June 2026

Overview

Hyperlipidemia is a metabolic condition characterized by elevated concentrations of lipids in the blood, including cholesterol carried in low-density lipoprotein, triglycerides, or both, often accompanied by reduced high-density lipoprotein. It arises from primary (genetic) causes such as familial combined hyperlipidemia and familial hypercholesterolemia, and from secondary causes related to diet, obesity, insulin resistance, and other metabolic and endocrine disorders. As a core component of the metabolic syndrome, hyperlipidemia is a major modifiable risk factor for atherosclerotic cardiovascular disease, promoting deposition of lipid within arterial walls, endothelial dysfunction, and plaque formation. Its molecular pathogenesis involves dysregulated synthesis, transport, and clearance of lipoproteins, frequently linked to disordered glucose and energy metabolism. Diagnosis rests on the fasting lipid profile, and management combines lifestyle modification, dietary change, and weight reduction with pharmacological therapy, principally statins and other lipid-lowering agents. Research relevant to this area examines the molecular and metabolic basis of familial hyperlipidemia and its association with metabolic syndrome, comparisons of plant-derived hypolipidemic agents with statin therapy in experimental models, and the interplay of dyslipidemia with obesity, diabetes, and cardiovascular risk. The journal publishes peer-reviewed studies on the pathogenesis, experimental modelling, and treatment of disordered lipid metabolism and its cardiovascular consequences.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 80 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Hyperlipidemia, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Lipids (ISSN 2835-513X).

Journal editorial board
Chih-Sheng Chu · Taiwan Anu Puri · United States Hiroshi Yoshida · Japan

This page summarises published research for orientation; it is not medical or professional advice.