Valvular Diseases

Overview

Valvular diseases are disorders of the four heart valves – the mitral, tricuspid, aortic and pulmonary valves. These conditions can be benign or can lead to life-threatening complications and can impact the patients’ quality of life. Valvular diseases can cause regurgitation, which is the backward flow of blood, or obstruction which is the narrowing of the valve orifice. The significance of valvular diseases is that they can cause the heart to work inefficiently, causing an array of symptoms, including fatigue, dizziness, shortness of breath and even heart failure. Without proper management, valvular diseases can become life-threatening, and it is important that they are diagnosed and treated early. Several treatments exist for valvular diseases. Depending on the type and severity of the condition, a doctor may recommend lifestyle changes, medications, or a minimally invasive or open-heart surgery in order to treat the condition. Treatment can reduce the symptoms of valvular diseases, improve the quality of life for a patient, and even save the patient’s life. This highlights the importance of recognizing the early signs of valvular diseases and seeking medical attention as soon as possible. Regular checkups and screenings can help detect underlying health conditions and can allow for early diagnosis and treatment. Valvular diseases can be managed with careful attention in order to prevent serious health complications.

Research published in this journal

2 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 2 articles above have been cited 4 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

• Telotristat ethyl reverses myxomatous changes in mice mitral valves
  2022 · Frontiers in Cardiovascular Medicine
• Aggrecan in Cardiovascular Development and Disease
  2020 · Journal of Histochemistry & Cytochemistry
• Osteogenesis inducers promote distinct biological responses in aortic and mitral valve interstitial cells
  Xinmei Wang et al. · 2019 · Journal of Cellular Biochemistry
• Loss of β-Catenin Promotes Chondrogenic Differentiation of Aortic Valve Interstitial Cells
  2014 · Arteriosclerosis, Thrombosis, and Vascular Biology

A sample of recent works citing this journal's research on Valvular Diseases, linking to each citing work.

This page summarises published research for orientation; it is not medical or professional advice.

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