Research Topic · Peer-Reviewed

Gene Expression

Gene expression is the process by which the information encoded in a gene is converted into a functional product, typically through transcription of DNA into RNA and translation of messenger RNA into protein. It is tightly regulated at multiple levels, including transcription-factor binding, epigenetic modification,…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 71× across the literature

Overview

Gene expression is the process by which the information encoded in a gene is converted into a functional product, typically through transcription of DNA into RNA and translation of messenger RNA into protein. It is tightly regulated at multiple levels, including transcription-factor binding, epigenetic modification, and post-transcriptional control by molecules such as microRNAs, allowing cells to respond to internal and environmental signals and to maintain specialized function. Research in this area examines transcriptional regulation, including the activation of transcription factor EB and NF-κB-mediated control in keratinocytes, and the modulation of cytokine gene expression by viral proteins. Studies of gene-expression analysis identify mechanisms of resistance to apoptosis in colorectal cancer and characterize the expression of adhesion molecules such as VCAM-1 in tumor tissue. MicroRNA-mediated regulation is explored through direct promoter targeting of genes such as OCT4 and the quantification of microRNAs for diagnostic screening. Other work addresses regulatory single-nucleotide polymorphisms and transcription-factor binding sites in disease and adaptation, the epigenetic regulation of neurotrophic factors in chronic pain, and the evolutionary conservation of developmental gene families. The role of specific genes in chronic kidney disease and thyroid cancer proliferation further illustrates the field's scope. By elucidating how genes are switched on and off and translated into function, the study of gene expression underpins understanding of development, disease mechanisms, and molecular diagnostics.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 71 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.

A sample of recent works citing this journal's research on Gene Expression, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Inflammation Research.

Journal editorial board
Frederic Velard · France Graziella Curtale · Italy Jincheng Zeng · China

This page summarises published research for orientation; it is not medical or professional advice.