Research Topic · Peer-Reviewed

Voxel-based Morphometry

Voxel-based morphometry (VBM) is a neuroimaging analysis technique used to investigate differences in brain anatomy from magnetic resonance imaging data. Rather than focusing on predefined regions, VBM compares brain structure across the whole brain on a voxel-by-voxel basis, allowing researchers to detect localized…

Curated from this journal's research 📚 1 peer-reviewed article cited Cited 9× across the literature 🔖 ISSN 2577-2279 🗓 Reviewed June 2026

Overview

Voxel-based morphometry (VBM) is a neuroimaging analysis technique used to investigate differences in brain anatomy from magnetic resonance imaging data. Rather than focusing on predefined regions, VBM compares brain structure across the whole brain on a voxel-by-voxel basis, allowing researchers to detect localized differences in features such as gray matter and white matter volume or concentration between groups or over time. The method involves spatially normalizing individual brain images to a common template, segmenting tissue types, smoothing the data, and performing statistical comparisons at each voxel. Because it is automated and unbiased with respect to location, VBM is widely applied in research on neurological and psychiatric conditions, aging, and development, where it can reveal patterns of regional atrophy or structural change associated with disease, cognition, or behavior. As a quantitative tool for characterizing brain morphology, VBM complements other imaging and anatomical methods in linking structural changes to clinical and functional outcomes. The study of human anatomy, including the structure of the brain and the techniques used to measure it, provides the foundation for interpreting such imaging-based assessments. This page gathers peer-reviewed, open-access research relevant to the topic.

Research published in this journal

1 peer-reviewed article, ranked by relevance. Each links to its DOI.

How this research is being cited

The 1 article above has been cited 9 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Voxel-based Morphometry, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Human Anatomy (ISSN 2577-2279).

Journal editorial board
Randy Kulesza · United States Bing Guoying · United States Shuji Kitahara · Japan

This page summarises published research for orientation; it is not medical or professional advice.