Metabolic syndrome is a clustering of interrelated cardiometabolic risk factors that together substantially raise the likelihood of type 2 diabetes and atherosclerotic cardiovascular disease. The defining components are central (abdominal) obesity, elevated blood pressure, raised fasting glucose, elevated triglyceri…
Metabolic syndrome is a clustering of interrelated cardiometabolic risk factors that together substantially raise the likelihood of type 2 diabetes and atherosclerotic cardiovascular disease. The defining components are central (abdominal) obesity, elevated blood pressure, raised fasting glucose, elevated triglycerides, and reduced HDL cholesterol, with insulin resistance and chronic low-grade inflammation regarded as central mechanisms linking adipose tissue dysfunction to systemic metabolic disturbance. Epidemiological investigation focuses on prevalence and determinants across occupational, clinical, and adolescent populations, including its frequency among patients receiving antipsychotic or antidepressant medication, where treatment-related metabolic effects compound underlying risk. Anthropometric indices of central obesity are evaluated as practical predictors of metabolic risk, reflecting the syndrome's grounding in body-fat distribution and adipose tissue physiology. Research also addresses molecular and familial contributions, such as combined hyperlipidemia, and overlap with related conditions including polycystic ovary syndrome and menopausal cardiovascular risk. A substantial line of work examines dietary and nutritional management, evaluating antioxidant micronutrients, specific foods, and supplements for their effects on insulin sensitivity, lipid and glucose handling, and postprandial metabolism. Because its components are modifiable, metabolic syndrome is approached as a target for early identification and combined lifestyle and pharmacological intervention to prevent progression to overt disease.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 24 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Metabolic Syndrome, linking to each citing work.