Sherlock One-pot Testing

The International Journal of Coronaviruses is an online peer-reviewed journal dedicated to the advances in research on the Coronaviruses. Coronavirus is a type of virus family that causes respiratory illness ranging from the common cold to more severe diseases such as Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). The Coronavirus Disease 2019 (COVID-19) caused by the SARS-CoV-2 virus has recently caused a pandemic, affecting millions of people globally. Researchers have been working tirelessly to understand the virus, develop effective treatments, and vaccines. One of the essential steps in this process is accurate and rapid diagnosis. Sherlock One-pot Testing is a novel technology that can detect SARS-CoV-2 virus in patient samples rapidly. This technology uses CRISPR-Cas13, an RNA-guided RNA endonuclease, to detect the viral RNA. The innovative one-pot protocol streamlines the process of RNA extraction and amplification, reducing the time needed for testing. The assay can detect the viral RNA within an hour, making it a valuable tool in the fight against COVID-19. The Sherlock One-pot Testing technology has been developed by a team of researchers from the Broad Institute of MIT and Harvard, and is licensed to Sherlock Biosciences, a company that aims to democratize access to molecular diagnostics. The technology has received emergency use authorization (EUA) from the US Food and Drug Administration (FDA) and is being used in various settings, including clinics and research laboratories. In conclusion, the Sherlock One-pot Testing technology is a promising development in the field of coronavirus diagnosis. Its rapid and accurate results make it a valuable tool in the fight against COVID-19. The International Journal of Coronaviruses will continue to publish relevant research and advancements related to this ongoing pandemic.