Overview
Covid variant molecular mechanisms refer to the genetic and biochemical processes by which SARS-CoV-2, the virus that causes COVID-19, accumulates mutations and gives rise to new variants with altered properties. As the virus replicates, changes in its genome, particularly in the spike glycoprotein gene, can affect how efficiently it binds to host cells, evades immune responses, and spreads through populations. Understanding these molecular mechanisms, including the patterns of mutation and selection that drive viral evolution, is central to anticipating new variants and refining diagnostic, therapeutic, and public health strategies. Within the International Journal of Coronaviruses, related work includes a molecular evolutionary analysis of SARS-CoV-2 spike glycoprotein-coding gene sequences from cases in Tunisia, compared with other human and animal coronaviruses, and a computational study presenting an algorithm to predict possible SARS-CoV-2 mutations. The journal has also published research on how the SARS-CoV-2 spike protein influences interferon and cytokine gene expression, addressing the protein at the center of variant biology. This page gathers peer-reviewed, open-access research relevant to the molecular mechanisms underlying COVID-19 variant emergence and evolution.
Research published in this journal
10 peer-reviewed articles, ranked by relevance. Each links to its DOI.
How this research is being cited
The 10 articles above have been cited 18 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2024 · German Journal of Pharmaceuticals and Biomaterials
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2024 · Archives of Pulmonology and Respiratory Care
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2023 · Revista Brasileira de Farmacognosia
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2023 · Revista Brasileira de Farmacognosia
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Satadal Das et al. · 2023 · International Journal of Applied Biology
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2023 · Análisis Político
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2023 · Applied Mathematics and Nonlinear Sciences
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2023 · Análisis Político
A sample of recent works citing this journal's research on Covid Variant Molecular Mechanisms, linking to each citing work.