Overview
Broth microdilution is a standardized laboratory method used in clinical microbiology to determine how susceptible a bacterium or fungus is to a particular antimicrobial agent. In the test, a series of small wells, typically in a microtiter plate, contains a liquid growth medium with progressively decreasing concentrations of the drug. Each well is inoculated with the microorganism and incubated, after which the wells are examined for visible growth. The lowest concentration that prevents visible growth is recorded as the minimum inhibitory concentration, or MIC, a key quantitative measure of antimicrobial activity. Broth microdilution is widely regarded as a reference method for susceptibility testing because it yields precise, reproducible MIC values that guide the selection of effective therapy and help detect and track antimicrobial resistance. International Journal of Clinical Microbiology publishes peer-reviewed research relevant to antimicrobial susceptibility and resistance, including studies of carbapenem resistance and antibiotic susceptibility patterns in Klebsiella pneumoniae, molecular detection of resistance genes in urinary tract infections, and the in vitro activity of agents such as iclaprim against resistant Staphylococcus aureus. This page gathers open-access research relevant to broth microdilution, MIC determination, and the laboratory evaluation of antimicrobial agents.
Research published in this journal
4 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Growing Threat Increased Carbapenem-Resistance among Klebsiella pneumoniae; Antibiotic Susceptibility Pattern of Klebsiella pneumoniae in a Tertiary Care Hospital
The Development and Evaluation of A Multiplex Real-Time PCR Assay for the Detection of ESBL Genes in Urinary Tract Infections
In Vitro Activity of Iclaprim Against Methicillin-Resistant Staphylococcus aureus Nonsusceptible to Daptomycin, Linezolid or Vancomycin
How this research is being cited
The 4 articles above have been cited 18 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2024 · PLoS ONE
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Solomon O. Olorunleke et al. · 2024 · PLoS ONE
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2023 · Selçuk tıp dergisi/Selçuk Üniversitesi Tıp Fakültesi dergisi
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Fatimah E. Alquraishi et al. · 2022 · International Journal of Health Sciences
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Aya A. Al-Baz et al. · 2022 · The Egyptian Journal of Hospital Medicine
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2022 · JAC-Antimicrobial Resistance
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2022 ·
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P. Bidet et al. · 2022 · JAC-Antimicrobial Resistance
A sample of recent works citing this journal's research on Broth Microdilution, linking to each citing work.