Overview
Antimicrobials are agents that kill or inhibit the growth of microorganisms, encompassing antibacterials, antivirals, antifungals, and antiparasitics used to prevent and treat infection. They are classified by the organisms they target, by chemical structure and mechanism of action, and by whether they are microbicidal or microbistatic, with antibacterials further grouped by targets such as the cell wall, protein synthesis, nucleic acids, or metabolic pathways. A central concern surrounding their use is antimicrobial resistance, in which microbes evolve mechanisms that render once-effective drugs inactive; carbapenem resistance in Klebsiella pneumoniae and Escherichia coli, and multidrug resistance in Salmonella, illustrate how resistant organisms emerge, spread, and persist, sometimes forming biofilms that further reduce susceptibility. Resistance is driven by selective pressure from antimicrobial use across human medicine, veterinary practice, and the community, including self-medication and inappropriate prescribing. Countermeasures include antimicrobial stewardship, restriction policies in high-risk settings such as neonatal units, surveillance of susceptibility patterns, and the search for new compounds, including agents derived from natural products. Understanding the spectrum, mechanism, and appropriate deployment of antimicrobials, together with the genotypic and phenotypic basis of resistance, is essential to preserving their effectiveness and protecting public health.
Research published in this journal
9 peer-reviewed articles, ranked by relevance. Each links to its DOI.
How this research is being cited
The 9 articles above have been cited 35 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Infection
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2025 · BMC Infectious Diseases
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Lidya Hafidzah Putri et al. · 2025 · JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
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Factors influencing irresponsible self-medication in rural Ethiopia: Insights from Gimbichu district2025 · Journal of Public Health in Africa
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2025 · PLOS One
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2025 · Frontiers in Microbiology
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2025 · Open Forum Infectious Diseases
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2025 · Frontiers in Microbiology
A sample of recent works citing this journal's research on Antimicrobials, linking to each citing work.