Overview
Osteocalcin is a non-collagenous protein produced by osteoblasts and found in bone and dentin, where it plays a role in bone mineralization and calcium regulation. Research published in the International Journal of Bone and Mineral Metabolism has examined osteocalcin in contexts ranging from dental implant surface modification to toxicological assessment of bone-affecting substances. One study explored the potential use of microRNAs as activators of dental implant surfaces, addressing how molecular signaling pathways involving osteocalcin and other bone markers might enhance osseointegration. Another investigation focused on establishing minimal risk levels for cadmium exposure, a heavy metal known to interfere with bone metabolism; this work considered cadmium's effects on skeletal health markers including osteocalcin across acute and intermediate exposure durations. These studies reflect the protein's significance as both a functional component of mineralized tissues and a biomarker for assessing bone health and metabolic disturbances. Understanding osteocalcin's regulation and response to environmental factors and therapeutic interventions remains important for advancing bone tissue engineering, evaluating toxic exposures, and developing strategies to promote skeletal integrity in clinical and occupational health settings.
Research published in this journal
2 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Minimal Risk Level Derivation for Cadmium: Acute and Intermediate Duration Exposures
How this research is being cited
The 2 articles above have been cited 11 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Toxics
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2025 · Toxics
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2025 · Atmosphere
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2025 · Journal of Environmental Exposure Assessment
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2025 · Atmosphere
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2025 · Toxics
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2025 · Journal of Environmental Exposure Assessment
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2025 ·
A sample of recent works citing this journal's research on Osteocalcin, linking to each citing work.