Research Topic · Peer-Reviewed

Osteocalcin

Osteocalcin is a non-collagenous protein produced by osteoblasts and found in bone and dentin, where it plays a role in bone mineralization and calcium regulation. Research published in the International Journal of Bone and Mineral Metabolism has examined osteocalcin in contexts ranging from dental implant surface m…

Curated from this journal's research 📚 2 peer-reviewed articles cited Cited 11× across the literature 🗓 Reviewed June 2026

Overview

Osteocalcin is a non-collagenous protein produced by osteoblasts and found in bone and dentin, where it plays a role in bone mineralization and calcium regulation. Research published in the International Journal of Bone and Mineral Metabolism has examined osteocalcin in contexts ranging from dental implant surface modification to toxicological assessment of bone-affecting substances. One study explored the potential use of microRNAs as activators of dental implant surfaces, addressing how molecular signaling pathways involving osteocalcin and other bone markers might enhance osseointegration. Another investigation focused on establishing minimal risk levels for cadmium exposure, a heavy metal known to interfere with bone metabolism; this work considered cadmium's effects on skeletal health markers including osteocalcin across acute and intermediate exposure durations. These studies reflect the protein's significance as both a functional component of mineralized tissues and a biomarker for assessing bone health and metabolic disturbances. Understanding osteocalcin's regulation and response to environmental factors and therapeutic interventions remains important for advancing bone tissue engineering, evaluating toxic exposures, and developing strategies to promote skeletal integrity in clinical and occupational health settings.

Research published in this journal

2 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2018

The Use of Mirnas as Activators of Dental Implant Surfaces, A Review

Di Gianfilippo RiccardoCorresponding author
The University of Michigan - School of Dentistry, Department of Periodontics and Oral Medicine, 1011 North University Avenue, 48109-1078, Ann Arbor, MI – USA
Exact topic International Journal of Bone and Mineral Metabolism

How this research is being cited

The 2 articles above have been cited 11 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Osteocalcin, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Bone and Mineral Metabolism.

Journal editorial board
Riccardo Di Gianfilippo · Switzerland Monica Montesi · Italy Sunil Dr. Wimalawansa · United States

This page summarises published research for orientation; it is not medical or professional advice.