Research Topic · Peer-Reviewed

Antibody Response

The antibody response is the adaptive humoral immune reaction in which exposure to an antigen drives the production of specific antibodies by B lymphocytes and their plasma cell progeny. It begins with antigen recognition and B-cell activation, generally with T-helper-cell cooperation, followed by clonal expansion, …

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 35× across the literature 🗓 Reviewed June 2026

Overview

The antibody response is the adaptive humoral immune reaction in which exposure to an antigen drives the production of specific antibodies by B lymphocytes and their plasma cell progeny. It begins with antigen recognition and B-cell activation, generally with T-helper-cell cooperation, followed by clonal expansion, germinal-center reactions, class-switch recombination, and affinity maturation through somatic hypermutation. The primary response is dominated initially by IgM and later IgG, while a secondary response, mediated by memory B cells, is faster, of higher affinity, and of greater magnitude—the immunological basis of vaccination. Quantitative and qualitative measures, including antibody titer, seroconversion, neutralizing capacity, and immunoglobulin class, characterize the response and inform assessment of vaccine efficacy and seroprevalence. Antibody responses confer protection against viral and bacterial infection, can be probed serologically, and may be dysregulated in autoimmune syndromes. The research reflected here addresses immune responses to vaccination in calves and human cohorts, neutralizing antibodies in immune plasma, COVID-19 vaccine efficacy and post-vaccination seroprevalence, serological testing, and immunoassay methods such as the enzyme-linked immunosorbent assay. The journal publishes peer-reviewed studies on humoral immunity, vaccine-induced antibody responses, and serological assessment across human and veterinary settings.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2024

Splenectomy Reports

Exact topic Spleen And Liver Research doi:10.14302/issn.2578-2371.jslr-24-5157

How this research is being cited

The 12 articles above have been cited 35 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Antibody Response, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Anesthesia.

Journal editorial board
John Bebawy · United States Pradipta Bhakta · Ireland Mainul Haque · United Kingdom

This page summarises published research for orientation; it is not medical or professional advice.