Research Topic · Peer-Reviewed

Antibiotic Resistance

Antibiotic resistance is the capacity of bacteria to survive and proliferate in the presence of antimicrobial drugs that would otherwise inhibit or kill them. It arises through genetic mutation and the horizontal transfer of resistance determinants on plasmids, transposons, and integrons, and is propagated by select…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 52× across the literature 🗓 Reviewed June 2026

Overview

Antibiotic resistance is the capacity of bacteria to survive and proliferate in the presence of antimicrobial drugs that would otherwise inhibit or kill them. It arises through genetic mutation and the horizontal transfer of resistance determinants on plasmids, transposons, and integrons, and is propagated by selective pressure from antibiotic exposure in clinical and agricultural settings. The principal biochemical mechanisms include enzymatic inactivation of the drug, such as the beta-lactamases and the extended-spectrum and carbapenem-hydrolyzing enzymes; modification or protection of the drug target; reduced membrane permeability; and active efflux. Clinically important resistant phenotypes include carbapenem-resistant Enterobacterales such as Klebsiella pneumoniae, methicillin-resistant Staphylococcus aureus, and multidrug-resistant uropathogens, which compromise the treatment of common and life-threatening infections. Detection relies on phenotypic susceptibility testing and molecular assays, including real-time PCR for resistance genes, while containment depends on antimicrobial stewardship, surveillance, infection prevention, and rational prescribing. The research reflected here spans susceptibility patterns in hospital pathogens, prescribing practices and stewardship across primary and tertiary care, resistance in vulnerable populations, and the interplay between resistance, surgical site infection, and other co-circulating diseases. The journal publishes peer-reviewed studies on the epidemiology, mechanisms, and clinical management of antimicrobial resistance.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 52 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Antibiotic Resistance, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Anesthesia.

Journal editorial board
John Bebawy · United States Pradipta Bhakta · Ireland Mainul Haque · United Kingdom

This page summarises published research for orientation; it is not medical or professional advice.