Research Topic · Peer-Reviewed

Anesthesia

Anesthesia is the controlled, reversible loss of sensation or awareness induced pharmacologically to permit surgical, diagnostic, and other medical procedures without pain or distress. It is broadly classified into general anesthesia, which produces unconsciousness and global suppression of sensation; regional anest…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 16× across the literature 🗓 Reviewed June 2026

Overview

Anesthesia is the controlled, reversible loss of sensation or awareness induced pharmacologically to permit surgical, diagnostic, and other medical procedures without pain or distress. It is broadly classified into general anesthesia, which produces unconsciousness and global suppression of sensation; regional anesthesia, including spinal, epidural, and peripheral nerve blocks, which interrupts conduction in defined nerve territories; and local anesthesia, which abolishes sensation in a small area. The principal drug classes are inhalational agents such as nitrous oxide and the halogenated volatiles, intravenous hypnotics such as propofol, opioid analgesics such as fentanyl, and local anesthetics of the amide and ester groups, including bupivacaine, which block voltage-gated sodium channels to prevent nerve impulse propagation. General anesthetics chiefly enhance inhibitory GABA-A receptor activity while modulating excitatory glutamatergic transmission. Clinical anesthesiology integrates agent selection, airway and ventilatory support, hemodynamic monitoring, and management of adverse events, and extends to investigation of anesthetic neurotoxicity, novel sodium-channel modulators, and predictors of perioperative complications. Beyond surgery, these principles underpin pain management and critical care. The journal publishes peer-reviewed research addressing anesthetic agents, regional techniques, perioperative monitoring, and the prevention of adverse events across diverse surgical settings.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 16 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Anesthesia, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Anesthesia.

Journal editorial board
John Bebawy · United States Pradipta Bhakta · Ireland Mainul Haque · United Kingdom

This page summarises published research for orientation; it is not medical or professional advice.