Isodesmosine

Isodesmosine, also known as Isostreptosin, is a peptide composed of two amino acids (glycine and leucine) commonly found in connective tissue and tendons. It is found at elevated levels in certain collagen diseases, like Ehlers-Danlos Syndrome and Marfan Syndrome, in which the tissue is not able to properly form its components due to genetic mutations. This peptide can be measured in either blood or urine and is used to diagnose and monitor these diseases, as well as monitor the progression of related treatments. As a biomarker, it has been found to be highly effective at accurately assessing the health of connective tissues. Therefore, it is an invaluable tool in the detection, diagnosis, and treatment of collagen-related diseases.