Research Topic · Peer-Reviewed

Hypersensitivity

Hypersensitivity is an exaggerated or inappropriate immune response to a substance that is normally harmless or only mildly threatening, resulting in tissue damage or uncomfortable symptoms. In immunology, hypersensitivity reactions are traditionally classified into four types: immediate IgE-mediated reactions that …

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 55× across the literature 🗓 Reviewed June 2026

Overview

Hypersensitivity is an exaggerated or inappropriate immune response to a substance that is normally harmless or only mildly threatening, resulting in tissue damage or uncomfortable symptoms. In immunology, hypersensitivity reactions are traditionally classified into four types: immediate IgE-mediated reactions that underlie allergies such as hay fever, asthma, and anaphylaxis; antibody-mediated cytotoxic reactions; immune complex-mediated reactions; and delayed, cell-mediated reactions such as contact dermatitis. Triggers, known as allergens, can include pollens, foods, drugs, insect venoms, and chemicals, and reactions range from mild itching, swelling, and rashes to severe, life-threatening responses. As a journal devoted to allergy, this page is supported by on-topic peer-reviewed work. Studies indexed here include an investigation of cross-reactivity between COX-2 inhibitors in patients with cross-reactive hypersensitivity to NSAIDs, a multicentre survey of contact hypersensitivity to lavender oil in Hungary, and a case of delayed allergy after cyanoacrylate closure of varicose veins diagnosed by a drug-induced lymphocyte stimulation test. Together these open-access articles illustrate the diversity of hypersensitivity reactions, including drug hypersensitivity and contact allergy, and the diagnostic approaches used to identify them, consistent with the journal's focus on allergic and immune-mediated disease.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 55 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Hypersensitivity, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Allergy.

Journal editorial board
Bobette Matulonga · France

This page summarises published research for orientation; it is not medical or professional advice.