Pulmonary hypertension is a haemodynamic disorder defined by abnormally elevated blood pressure within the pulmonary arterial circulation, which increases right ventricular afterload and, if sustained, leads to right heart strain and failure. It arises through diverse mechanisms including remodelling and narrowing o…
Pulmonary hypertension is a haemodynamic disorder defined by abnormally elevated blood pressure within the pulmonary arterial circulation, which increases right ventricular afterload and, if sustained, leads to right heart strain and failure. It arises through diverse mechanisms including remodelling and narrowing of the pulmonary arterioles, chronic hypoxaemia, left heart disease, thromboembolic obstruction, and systemic conditions that affect the pulmonary vasculature. Clinically it manifests as progressive dyspnoea, reduced exercise tolerance, and signs of right ventricular dysfunction, and its assessment relies on echocardiographic estimation of tricuspid regurgitant velocity alongside confirmatory testing. The condition frequently coexists with other cardiopulmonary and haematological disorders, which complicates diagnosis and management. Research gathered here reflects these intersections, examining pulmonary hypertension in an elderly HIV-infected population, the predictors of elevated tricuspid regurgitant velocity in sickle cell anaemia, comorbidities across chronic obstructive pulmonary disease phenotypes, and the broader spectrum of heart failure and congenital cardiac and diaphragmatic anomalies that influence pulmonary pressures. Additional contributions address microRNAs as diagnostic and therapeutic tools in hypertension and cardiorenal signalling pathways in heart failure. Collectively these peer-reviewed studies span the cardiovascular, respiratory, and systemic contexts in which pulmonary hypertension develops and is evaluated.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 17 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Pulmonary Hypertension, linking to each citing work.