Research Topic · Peer-Reviewed

Autoimmune Diseases

Autoimmune diseases are disorders in which the immune system loses tolerance to the body's own constituents and mounts a sustained attack against self-antigens, mediated by autoreactive T and B lymphocytes and self-directed autoantibodies. They are conventionally divided into organ-specific forms, in which damage is…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 50× across the literature 🔖 ISSN 2577-137X 🗓 Reviewed June 2026

Overview

Autoimmune diseases are disorders in which the immune system loses tolerance to the body's own constituents and mounts a sustained attack against self-antigens, mediated by autoreactive T and B lymphocytes and self-directed autoantibodies. They are conventionally divided into organ-specific forms, in which damage is confined to a particular tissue or gland, and systemic forms, in which autoimmunity affects multiple organs. Pathogenesis reflects an interplay of genetic susceptibility, prominently within the human leukocyte antigen (HLA) region, and environmental triggers such as infections, microbial exposures, and other stimuli, which together drive the chronic inflammation that produces tissue injury; this gene-inflammation-environment triad is central to current understanding. Conditions may cluster, as in autoimmune polyglandular syndromes that combine multiple endocrine and neuroimmunological targets, and immune dysregulation can also follow events including post-vaccination immune activation. Modifying factors such as vitamin D status are studied in mucosal and inflammatory conditions, while diagnosis relies on detecting circulating autoantibodies and characterizing immune activity through immunoassays, immunogenomics, and broader immunomonitoring. Representative disorders span endocrine, haematological, gastrointestinal, and mucocutaneous systems. The journal publishes peer-reviewed research addressing the gene-environment-inflammation basis of autoimmunity, polyglandular and neuroimmune overlap syndromes, the role of vitamin D, and immunomonitoring approaches to autoimmune disease.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2015

Epigenetics and Nutrition

Exact topic International Journal of Nutrition Cited by 2 doi:10.14302/issn.2379-7835.ijn-14-603

How this research is being cited

The 12 articles above have been cited 50 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Autoimmune Diseases, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Immunization (ISSN 2577-137X).

Journal editorial board
Giuseppe Murdaca · Italy Harunor Rashid · Australia Ming Tan · United States

This page summarises published research for orientation; it is not medical or professional advice.