Overview
Heart development refers to the complex biological processes through which the heart forms and matures, beginning in early embryonic stages and continuing through fetal growth and postnatal adaptation. Research published in this journal addresses multiple dimensions of cardiac development and disease, including the molecular mechanisms governing human embryonic development, the role of microRNAs as potential therapeutic targets in ischemic heart disease, and structural abnormalities that arise during valve formation. Studies have examined how human myxomatous mitral valves express cartilage-related proteins, revealing insights into developmental pathways that may contribute to valve disease. Additional work has explored genetic polymorphisms in genes such as PAR-α and tissue factor that influence coronary heart disease risk in specific populations. Understanding heart development is essential because congenital heart defects remain among the most common birth abnormalities, and developmental processes often recapitulate in adult cardiac remodeling and disease. By investigating the molecular controls, genetic factors, and cellular mechanisms underlying normal and abnormal heart formation, researchers aim to identify new therapeutic strategies and improve outcomes for patients with both congenital and acquired cardiac conditions.
Research published in this journal
4 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Human Myxomatous Mitral Valves Exhibit Focal Expression of Cartilage-Related Proteins
Molecular Control of Human Embryonic Development: A Comprehensive Study
L162v Polymorphism of Par-Α Gene, A603g Polymorphism of Tissue Factor Gene and Risk of Coronary Heart Disease in Russian Population
How this research is being cited
The 4 articles above have been cited 11 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2025 · Journal of Genetic Engineering and Biotechnology
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A. A. Raeef et al. · 2025 · Journal of Genetic Engineering and Biotechnology
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2022 · Cureus
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Aykut Kemancı et al. · 2022 · Cureus
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2022 · Frontiers in Cardiovascular Medicine
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2020 · Journal of Histochemistry & Cytochemistry
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2019 · BioMed Research International
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2019 · BioMed Research International
A sample of recent works citing this journal's research on Heart Development, linking to each citing work.