Cardiovascular disease (CVD) is the broad class of disorders affecting the heart and blood vessels, encompassing coronary artery disease, heart failure, cerebrovascular disease, hypertensive heart disease, arrhythmias, and peripheral vascular disease. These conditions share overlapping pathophysiology, including ath…
Cardiovascular disease (CVD) is the broad class of disorders affecting the heart and blood vessels, encompassing coronary artery disease, heart failure, cerebrovascular disease, hypertensive heart disease, arrhythmias, and peripheral vascular disease. These conditions share overlapping pathophysiology, including atherosclerosis, endothelial dysfunction, and adverse cardiac remodelling, and a common constellation of modifiable risk factors such as hypertension, dyslipidemia, diabetes, smoking, obesity, and physical inactivity. CVD is also shaped by interactions between organ systems, notably cardiorenal signalling, in which dysfunction of the heart and kidneys propagates reciprocally, and by metabolic and acid-base disturbances that influence cardiac load and vascular health. Psychosocial dimensions, including depression, are recognised contributors to risk and outcome, while genetic susceptibility helps explain individual variation in disease onset and severity. Prevention spans lifestyle modification, particularly regular exercise, alongside pharmacological control of risk factors. Studies in this area examine the relationship between metabolic acidosis and cardiovascular disease in patients undergoing peritoneal dialysis, the identification of candidate genes for cardiovascular disease, associations between cardiovascular risk factors and depression, cardiorenal signalling mechanisms in heart failure, and the protective effects of exercise. The field integrates cardiology, nephrology, genetics, epidemiology, and behavioural science to address a leading cause of global morbidity and mortality.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 79 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Cardiovascular Disease, linking to each citing work.