Antibody specificity is the property by which an antibody recognises and binds to a particular target, its antigen, while largely ignoring other molecules. This selectivity arises from the precise fit between the antibody's variable binding region and a specific molecular feature, or epitope, on the antigen, and it …
Antibody specificity is the property by which an antibody recognises and binds to a particular target, its antigen, while largely ignoring other molecules. This selectivity arises from the precise fit between the antibody's variable binding region and a specific molecular feature, or epitope, on the antigen, and it underlies the immune system's ability to distinguish foreign substances and direct responses against them. High specificity is essential both to natural immunity and to the many laboratory and clinical applications that depend on antibodies, including diagnostic assays, disease monitoring, and targeted therapies, where binding to the wrong molecule can cause false results or unwanted effects. Characterising and controlling specificity is therefore a central concern in immunology and biomedical research. Studies published in Human Health Research and related journals reflect this, including a review of current immunoassays and emerging immunogenomic approaches for immunomonitoring cancer and infectious diseases, which depend on antibodies binding their intended targets, and a history of the development of the enzyme-linked immunosorbent assay, a widely used antibody-based detection method. Together these illustrate how antibody recognition is harnessed for measurement and diagnosis. This page gathers peer-reviewed, open-access research relevant to antibodies, antigen recognition, and immunological detection methods.
7 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 7 articles above have been cited 16 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Antibody Specificity, linking to each citing work.