Research Topic · Peer-Reviewed

Suppressor Genes

Suppressor genes, also known as tumor suppressor genes or anti-oncogenes, are a group of genes that play a critical role in regulating cell growth and preventing the development of cancer. These genes are responsible for maintaining the normal cell cycle by inhibiting the overgrowth and malignant transformation of c…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 24× across the literature 🔖 ISSN 2372-6601 🗓 Reviewed June 2026

Overview

Suppressor genes, also known as tumor suppressor genes or anti-oncogenes, are a group of genes that play a critical role in regulating cell growth and preventing the development of cancer. These genes are responsible for maintaining the normal cell cycle by inhibiting the overgrowth and malignant transformation of cells. The mutations in suppressor genes can lead to the loss or reduction of their function, causing abnormal cell growth and proliferation, and therefore increasing the risk of cancer. One of the most well-known suppressor genes is the p53 gene, which is often referred to as the "guardian of the genome" due to its role in DNA repair and cell cycle regulation. Mutations in the p53 gene have been identified in many types of cancers and are linked to the progression of the disease. Other suppressor genes include BRCA1 and BRCA2, which are associated with an increased risk of breast and ovarian cancer when mutated, and APC (Adenomatous polyposis coli), which is responsible for suppressing the development of colon tumors. Research in hematology and oncology focuses on understanding the function of suppressor genes and how their mutations contribute to the development and progression of cancer. The identification of these genes has led to the development of targeted therapies aimed at restoring their function in cancer cells and preventing tumor growth. In conclusion, suppressor genes are critical in preventing the development of cancer, and their study plays an important role in advancing the field of hematology and oncology research.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2019

Genes in Tumor Formation

Exact topic Hematology and Oncology Research Cited by 2 doi:10.14302/issn.2372-6601.jhor-19-2986
2015

Epigenetics and Nutrition

Exact topic International Journal of Nutrition Cited by 2 doi:10.14302/issn.2379-7835.ijn-14-603

How this research is being cited

The 12 articles above have been cited 24 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Suppressor Genes, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Hematology and Oncology Research (ISSN 2372-6601).

Journal editorial board
Jayadev Manikkam Umakanthan · United States Shuaiying Cui · United States Benedetto Sacchetti · Italy

This page summarises published research for orientation; it is not medical or professional advice.