Research Topic · Peer-Reviewed

Ovarian Cancer

Ovarian cancer is a malignant neoplasm arising in the ovary, encompassing epithelial carcinomas, which account for the majority of cases, as well as germ cell and sex cord-stromal tumors. Epithelial ovarian cancer is histologically and molecularly heterogeneous, with high-grade serous carcinoma frequently driven by …

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 41× across the literature 🔖 ISSN 2372-6601 🗓 Reviewed June 2026

Overview

Ovarian cancer is a malignant neoplasm arising in the ovary, encompassing epithelial carcinomas, which account for the majority of cases, as well as germ cell and sex cord-stromal tumors. Epithelial ovarian cancer is histologically and molecularly heterogeneous, with high-grade serous carcinoma frequently driven by TP53 mutation and homologous recombination deficiency, including BRCA1 and BRCA2 alterations that confer hereditary risk and predict therapeutic sensitivity. Because early disease is often asymptomatic and produces nonspecific symptoms, it is commonly diagnosed at an advanced stage following peritoneal spread, which contributes to its high mortality among gynecologic malignancies. Management combines cytoreductive surgery with platinum-based chemotherapy and increasingly targeted and maintenance therapies, while research priorities include early detection, biomarker discovery, and characterization of genetic susceptibility. The journal publishes peer-reviewed research relevant to ovarian malignancy, including ovarian cancer identification through feature weighting of high-throughput mass spectrometry data, functional and structural analysis of a BRCA1 variant of uncertain clinical significance, steroid cell tumor of the ovary, coexistence of teratoma and endometrioma in an ovarian cyst, and pH-sensitive nanomedicine for treating gynaecological cancers. Related oncology work addresses microRNA-based and mass-spectrometry diagnostic approaches, oxidative and antioxidant influences on biological aging, and cancer cell biology, reflecting the diagnostic, genetic, and therapeutic challenges that characterize ovarian cancer.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2015

Epigenetics and Nutrition

Exact topic International Journal of Nutrition Cited by 2 doi:10.14302/issn.2379-7835.ijn-14-603

How this research is being cited

The 12 articles above have been cited 41 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Ovarian Cancer, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Hematology and Oncology Research (ISSN 2372-6601).

Journal editorial board
Jayadev Manikkam Umakanthan · United States Shuaiying Cui · United States Benedetto Sacchetti · Italy

This page summarises published research for orientation; it is not medical or professional advice.