Research Topic · Peer-Reviewed

Neoplastic Transformation

Neoplastic transformation is the process by which normal cells acquire genetic and molecular alterations that enable uncontrolled growth, leading to the formation of tumors or cancers. Research published in Hematology and Oncology Research addresses multiple dimensions of this phenomenon, examining both inherited ge…

Curated from this journal's research 📚 5 peer-reviewed articles cited Cited 16× across the literature 🔖 ISSN 2372-6601 🗓 Reviewed June 2026

Overview

Neoplastic transformation is the process by which normal cells acquire genetic and molecular alterations that enable uncontrolled growth, leading to the formation of tumors or cancers. Research published in Hematology and Oncology Research addresses multiple dimensions of this phenomenon, examining both inherited genetic susceptibilities and acquired transformations across diverse tissue types. The journal has explored hereditary syndromes such as multiple endocrine neoplasia type I, where germline mutations predispose individuals to multiple tumor formations, as well as virus-induced pathways of carcinogenesis, particularly the mechanisms by which human papillomavirus drives malignant transformation. Published studies have investigated rare neoplastic conditions including uterine leiomyosarcoma and chondrosarcoma, contributing to biomarker identification and elemental analysis of affected bone tissue. Additionally, the journal has documented cases of premalignant and benign proliferative conditions such as glandular and cystic bladder lesions that represent intermediate stages in the transformation spectrum. Understanding neoplastic transformation remains essential for developing early detection strategies, identifying at-risk populations, and elucidating the molecular events that distinguish benign proliferation from malignant progression across hematologic and solid organ malignancies.

Research published in this journal

5 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 5 articles above have been cited 16 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Neoplastic Transformation, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Hematology and Oncology Research (ISSN 2372-6601).

Journal editorial board
Jayadev Manikkam Umakanthan · United States Shuaiying Cui · United States Benedetto Sacchetti · Italy

This page summarises published research for orientation; it is not medical or professional advice.