Molecular Diagnostics and Targeted Cancer Therapies

Hematology and Oncology research have both revolutionized the approach to diagnosing and treating cancers. With advances in molecular diagnostic tools, clinicians can now detect cancer at its earliest stages and identify the specific genetic alterations driving the cancer's growth. This has led to the development of targeted cancer therapies. Molecular diagnostics refers to the use of biological markers, such as genetic mutations and changes in gene expression, to detect diseases. In the context of cancer, molecular diagnostics can provide critical information about the genetic makeup of a patient's tumor. This information can guide treatment decisions and predict a patient's response to therapy. Targeted cancer therapies use drugs or other agents to specifically target cancer cells, based on their unique molecular profiles. Unlike traditional chemotherapy, which kills both cancerous and healthy cells, targeted therapies aim to spare healthy cells and minimize side effects. These therapies have shown great promise in treating a variety of cancers, including lung, breast, and colon cancer. In addition to targeted therapies, there is a growing field of immunotherapy for cancer. Immunotherapy works by boosting the body's natural defenses to fight cancer. It uses substances made by the body or in a laboratory to improve or restore immune system function. This approach has shown significant success in treating some types of cancer, such as melanoma and certain blood cancers. In conclusion, the use of molecular diagnostics and targeted cancer therapies is transforming the field of Hematology and Oncology. The integration of these tools into clinical practice provides clinicians with essential information about cancer diagnosis and treatment, and allows for more personalized, effective cancer care. As research continues in these areas, we can expect even greater progress in the future for the prevention and treatment of cancer.

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120 article(s) found
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Evaluation of SterculiaUrens Gum as Novel Carrier for Oral Colon Targeted Drug Delivery System
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Molecular Cytogenetic Investigations in a Novel Chromosomal Abnormality of t(10;15)(q22;q22) in a Pediatric Precursor-B-Acute Lymphoblastic Leukemia Patient
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Factors that Influence Fenofibrate Effects on Cancer Cells
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Correlation of Oncotype DX Recurrence Score with the Expression of Insulin Receptor Substrate Proteins in Estrogen Receptor + Breast Cancer
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A Review of the Histologic, Genetic and Molecular Characteristics of Meningioma Pathogenesis and Progression
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Understanding Ubl-Rpn1 Intermolecular Interaction
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Diagnostics of Progressive Multifocal Leukoencephalopathy in a Patient with Concomitant Lymphoma Infiltration of Central Nervous System During R-CHOP Chemotherapy- A Case Presentation and Review of the Literature.
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Mechanisms Associated with Acquisition of Resistance to Butyrate-Induced Apoptosis in Colorectal Cancer Cells Using Gene Expression Analysis
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Current Status of Nonsteroidal Anti-Inflammatory Drugs in Colorectal Cancer Prevention
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First Evidences of Epithelial-Mesenchymal Transition and Cancer Stem-Cell Phenotype Acquisition in Dermo-Epidermal Junction of BPV-Infected Neoplasms
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Medullary Thyroid Cancer: Is the Adequacy of Pre-Operative Evaluation Influenced by Training Background?
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Overexpression of Prostate Apoptosis Response Protein-4 In Colon Cancer Cells Can Inhibit Metastasis by Upregulating E-cadherin Expression
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Evaluating Circadian Oscillators in Cancer Stem Cells
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Management of Locally Advanced and Metastatic Pediatric Nasopharyngeal Carcinoma. Experience of Children Cancer Hospital – Egypt
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Thyroid Transcription Factor-1 Activity is Required for the Proliferation of Human Thyroid Cancer Cells 8505C
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Metabolic Correction Therapy as Adjuvant Treatment for Breast Cancer Patients: A Case Report
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Investigations of Molecular Evolutionary Mechanisms in Partially Sequenced Heat Shock Protein70 Homologue-Coding Gene of Olive Leaf Yellowing-Associated Virus Isolates from Tunisia
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Taller Haustral Folds in the Proximal Colon: A Potential Factor Contributing to Interval Colorectal Cancer
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High expression of miR-21 in tissue correlated with the poor survival of patients with esophageal cancer: a pilot study using the meta-analysis
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Gene-Eden-VIR: A Potential Natural Treatment for Cervical Cancer
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GR-RNF43 Regulation in Colorectal Cancer
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Evidence that N-acetylaspartylglutamate is the Astrocyte-Targeted Neurovascular Coupling Agent that Regulates Slow Tonic Control of Brain Blood Flow
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Predictors Of Colon Cancer in Patients Referred to a Gastroenterologist for Iron Deficiency
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Correlates of Mental Health in Survivors of Colorectal Cancer: The Influence of Individual, Family, and Community Level Factors
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Prerequisites for Emergency Laparoscopic Surgery for Colorectal Cancer
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Emerging Paradigms in Regenerative Medicine: Stem cell Therapies
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Molecular Structure and Vibrational Analysis of 2-(4-methoxyphenyl)-2, 3-Dihydro-1H-Perimidine using Density Functional Theory
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A Deadly Combination: Depression and Suicide in the Presence of Cancer
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The Role of Heparin in Lung Cancer
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Compliance to Company Based Colorectal Cancer Screening in Germany using Fecal Immunochemical Test (FIT) - Results of Almost Half a Million FIT Tests
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Markers for Significant or High-Grade Prostate Cancer in Patients over 75 Years Undergoing Prostatic Biopsy
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Combined Therapy Versus Usual Care in the Treatment of Depressed Cancer Patients with Pain
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Left Brachiocephalic Vessel Venous Tumor Thrombus in a Laryngeal Cancer Patient Detected with PET-CT Imaging
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Study of VCAM-1 Gene Expression in Normal and Tumoral Tissues in Patients with Colorectal Cancer
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Cellular Mechanics and Therapeutic Resistance of the Cancer Relapse
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Molecular Spectroscopy and Molecular Docking Studies on (E)-1-(4-Bromobenzylidene) Thiourea
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Perspectives on Sub–Nanometer Level of Electronic Structure of the Synchrotron with Mendelevium Nanoparticles for Elimination of Human Cancer Cells, Tissues and Tumors Treatment Using Mathematica 12.0
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Efficacy of The Immunotargeting Therapeutic Antibody Trastuzumab in HER2-Positive Advanced Gastric Cancer: A Meta-Analysis
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Ovarian Cancer Identification Based on Feature Weighting for High-Throughput Mass Spectrometry Data
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Statins and Lung Cancer: A Review of Current Literature
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Investigation and Analysis on Mental Health State of Breast Cancer Patients in China
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Cancer Stem Cells: A Cause or A Consequence of Field Cancerization
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Oncolytic Viruses: Can be Applicable Tools for Cancer Therapy?
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Breast Cancer, Chemokines, And Metastasis: A Search for Decoy Ligands of the CXCR4 Receptor
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Molecular and Cell Biological Considerations in the Initiation and Development of Sporadic Non-Hereditary Solid Cancers  
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Perioperative Period is a Critical Gap for Minimal Residual Cancer Cells Progression and Therapy: Biological and Molecular Based Evidences
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Molecular Biomarkers: A Brief Review
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Epigenetic Biomarkers in Head and Neck Cancer 
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Demonstration of the Capabilities of Transabdominal Ultrasonography in Assessment of Structures and Functional Disorders of Locally Advanced Gastric Cancer of Diverse Localization
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Analysis of Clinical Prognostic Variables for Triple Negative Breast Cancer Histological Grading and Lymph Node Metastasis
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Why People With Liver (or hepatic ) Cancer Should Die in Short - Time?
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Preoperative and Postoperative N-terminal Pro B-type Natriuretic Peptide Levels Predict Cardiac Morbidity and Mortality in Patients Undergoing Colorectal Cancer Resection
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Quantification of Micrornas by Absolute Dpcr for the Diagnostic Screening of Colon Cancer
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The Current Immunoassays and Emerging Immunogenomic Approaches for Immunomonitoring Cancer and Infectious Diseases
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Secular Trend in the Incidence of Japanese Employees with Thyroid Cancer Undergoing Thyroidectomy from 2005 to 2014: a Retrospective Descriptive Study Using an Employment-Based Insurance Claims Database
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The Temporal World in Caregivers of Cancer Survivors: Intertextual Analysis of their Experiences about the Perception of Time Compared with Excerpts from the Book "Einstein's Dreams
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Molecular Survey on Symbiodinium of Some Scleractinean Coral Spp. and a Fire Coral sp. along the Red Sea of Egypt
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Long Non-Coding RNAs Emerging as Potential Epigenetic Biomarkers for Tobacco and/or Alcohol-Induced Head and Neck Cancer
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Complementary and Alternative Treatments for Cancer Prevention and Cure (Part 1)
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Avant Garde Alleviation -Cancer Immunotherapy
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D Allele and DD Genotype of I /D Polymorphism in The ACE Gene in Patients with Hypertension, Stroke And Cancer Prostate In Libreville: A Concern Given The High Frequencies of these Signatures in Gabonese Population
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Molecular Composition of and Potential Health Benefits Offered by Natural East African Virgin Sunflower Oil Products: A 400 MHz 1H NMR Analysis Study
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Lung Cancer and Isolated Adrenal Metastases: Different Disease?
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Lung Cancer and Isolated Adrenal Metastases: Different Disease?
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Developing Cellular & Molecular Biomarkers for Anti-Inflammatory Activities of Probiotic Bacteria in Fermented Foods
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Construction of Virtual Neuron and Consolidation of Sleep and Memory Process– A Molecular Docking and Biomathematical Approach
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Selective Cytotoxicity of Damsin Derivatives in Breast Cancer Cells
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Uptake of Cervical Cancer Screening Among Female Staff at the University College Hospital, Ibadan
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Assessment of Anticancer Effect of Alendronate in Breast Cancer: An In vitro Study
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Molecular and Metabolic Pathogenesis of Familial Combined Hyperlipidemia and Association with Metabolic Syndrome
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Dispositional Mindfulness, Perceived Stress, and Mental Well-Being in the Cancer Survivorship
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Using Prostatic Fluid Levels of Zinc to Bromine Concentration Ratio in Non-Invasive and Highly Accurate Screening for Prostate Cancer
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The Effect of Aqueous Extract of Ocimum gratissium (Linn) on 1, 2 - Dimethyl Hydrazine induced Colon Cancer in Male Wistar Rats
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pH-Sensitive Nanomedicine for Treating Gynaecological Cancers
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Global Health Involvement in Thyroid Cancer Incidence Increase
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Molecular Study of Hepcidin HAMP (-582A/G) Gene Polymorphisms and Measurement of Serum Hepcidin Level among Sudanese Patients with Anemia of Chronic Kidney Disease
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Use of Microfluidic Assays to Develop Reliable and Economic Nucleic Acid Application Technologies, Employing MicroRNAs for the Diagnostic Screening of Colon Cancer in Human Stool in Low-Resource Settings
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Molecular Analysis of 6-pyruvoyltetrahydropterin Synthase Gene in Atypical Phenylketonuric Egyptian Patients
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Aerobic Plate Count of Contaminants and Molecular Characterization of Eschereichia Coli in Raw Chicken Meat in Ismailia, Egypt
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Risk Factors Associated with Breast Cancer
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Use of Microfluidic Assays to Develop Reliable and Economic Nucleic Acid Application Technologies, Employing MicroRNAs for the Diagnostic Screening of Colon Cancer in Human Stool in Low-Resource Settings
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Awareness of Cervical Cancer Screening test Among Women of Child Bearing age in the Rural Area of Awo-Omamma, Imo State, Nigeria.
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Comparative Survival Assessment of Two-Dimension (2D) vs Three-Dimension (3D) Brachytherapy Treatment in Cervical Cancer: A Retrospective Case Control Study
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Survival among Breast Cancer Patients in a Tertiary Cancer Center in Brunei Darussalam
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Molecular Evolutionary Characteristics of the 2019 Novel Coronavirus (SARS-CoV-2) Contracted by Tunisian Citizens : Comparison and Relationship to Other Human and Animal Coronaviruses Based on Spike Glycoprotein-Coding Gene Sequences Analysis
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Palliative Care for Cancer Patients and their Relatives in Dutch Community-Based Psychosocial Support Centers (CBPSCs)
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Molecular Evolution of the Novel Coronavirus SARS-CoV-2
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Use of the Remaining Sample from the Panbio COVID-19 Antigen Rapid Test Device for the Molecular Screening of the SARS-CoV-2 Variant of Concern B.1.1.7
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Colorectal Cancer in Africa: Causes, Dietary Intervention, and Lifestyle Change
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One Out of Five Women Practiced Cervical Cancer Screening in Felege Hiwot Referral Hospital, Amhara, North West Ethiopia
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Principles and Constants of the Golden Proportion as a Criterion in Donosological Diagnostics of the Functional States of The Body and in the Assessment of the Probability of their Changes
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Six Fractal Codes of Biological Life Unifying ATOMS, WAVES and INFORMATION: Perspectives in Exobiology, Cancers Basic Research and Artificial Intelligence Biomimetism Decisions Making
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New Approach in Treatment of Cancer & Viral Infection by Apis Mellifera L Venom Extracts (Honeybees Venom)
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Challenger and Propose Novel Methods and Techniques for Prevention, Prognosis, Diagnosis, Imaging, Screening, Treatment and Management of Lung Cancer
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Targeting Mutational Landscape of TP53 in patients diagnosed with Oral Cancer living in Senegal
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A Cancer Theory: The Central Nervous System’s Adaptive Changes Make Chronic Diseases Incurable
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Tay-Sachs Disease: From Molecular Characterization to Ethical Quandaries and the Possibility of Genetic Medicine
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Molecular Detection of Mycoplasma Gallisepticum and Mycoplasma Synoviae Infection in Poultry
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Correlating 13C Isotope in Oligomeric Proanthocyanidins with their Anticancer Properties
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The Risk of Oropharyngeal Cancer from E-Cigarette Use: An Urgent Public Health Concern
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Molecular Confirmation of Staphylococci Strain’s Identification Isolated in the Hospital and University Center of Brazzaville, Republic of Congo
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Characterization of The Oncogeriatric Population Attended at the Arturo López Perez Foundation (Falp) Cancer Institute
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CERN Large Hadron Collider (LHC) Radiation Source for Magnetic Resonance Biospectroscopy in Metabolic and Molecular Imaging and Diagnosis of Cancer
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Challenger Treatment of Various Cancers with T Cells Engineering
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Effect of Protein and Energy-Dense Nutritional Supplement with Immunonutrients on Cachexia in Cancer Patients: An Open-Label, Single-Arm Study Among Indian Patients
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Chemotherapy after whole-brain radiotherapy: a prognostic factor for metastatic breast cancer
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A Roadmap to Developing a Population-Based Colorectal Cancer Screening Program in Oman
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Molecular Diagnosis in Clinical Management and Diagnosis of Thyroid Cancer
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Stratified Analysis of Factors Associated With Mortality in Patients With COVID-19 Based on Cancer and Diabetes
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Cervical Cancer with The Active And Stable PI3K/MTOR/AKT Pathway In Azerbaijan Patients
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The Heart Physiology in Fertile Female and The Heart Pathophysiology in Post Menopausal Female. The Contribution of Molecular Biology, Maintaining Cardiac Hemodinamy and Electrophysiology
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RBM45: Molecular, Cellular, and Evolutionary Biology
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Pancreatic cancer in a Non-Tertiary Center: CEA and Bilirubin More Predictive than CA 19-9 at Initial Presentation
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Molecular Control of Human Embryonic Development: A Comprehensive Study
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Proteomic and Genomic Techniques in Medical Research: Applications in Cancer, Diagnostics, and Personalized Medicine
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Uptake of Cervical Cancer Screening and Its Determinants among Refugee Women in Uganda: Insights from the Uganda Refugee Population-based HIV Impact Assessment
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Molecular Approaches for Assessing Some Iranian Freshwater Fish Species
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Retrospective Evaluation of Well Differentiated Thyroid Cancer Treatment Outcomes: 50 year experience at the University of Puerto Rico
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The Effectiveness of Cognitive-Analytic Therapy in Women Diagnosed with Breast Cancer and Post-Traumatic Stress Disorder
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