Research Topic · Peer-Reviewed

Metabolic Labeling

Metabolic labeling is a technique in which cells or organisms are grown in the presence of isotopically labeled nutrients that become incorporated into newly synthesized biomolecules, enabling their detection and quantification through mass spectrometry or other analytical methods. Research published in Glycomics An…

Curated from this journal's research 📚 3 peer-reviewed articles cited Cited 8× across the literature 🔖 ISSN 2572-5424 🗓 Reviewed June 2026

Overview

Metabolic labeling is a technique in which cells or organisms are grown in the presence of isotopically labeled nutrients that become incorporated into newly synthesized biomolecules, enabling their detection and quantification through mass spectrometry or other analytical methods. Research published in Glycomics And Metabolism has explored metabolic labeling applications across proteomics and imaging contexts. One study demonstrated the use of nitrogen-15 stable isotope labeling by amino acids in cell culture (SILAC) in mouse models for quantitative proteomics, allowing researchers to compare protein expression levels between different biological states. Another investigation examined broader methodologies for discovery and quantification in mass spectrometry-based proteomics, addressing how labeled compounds facilitate accurate measurement of protein abundance. Additionally, the journal has published work on synthesizing isotopically labeled small molecules, specifically a labeled rifabutin derivative designed as a potential imaging agent for Mycobacterium tuberculosis detection. These applications illustrate how metabolic labeling serves as a foundational tool for tracking biosynthetic pathways, quantifying molecular changes in disease and development, and developing diagnostic agents, bridging fundamental metabolism research with practical biomedical applications.

Research published in this journal

3 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2013

Quantitative Proteomics Using 15N SILAC Mouse

I. Chen EmilyCorresponding author
Stony Brook University, Proteomics Center, School Of Medicine, NY
Exact topic Proteomics and Genomics Research Cited by 4 doi:10.14302/issn.2326-0793.jpgr-13-252
2014

Discovery and Quantification in Mass Spectrometry-Based Proteomics

I. Chen EmilyCorresponding author
Proteomics Shared Resource at the Columbia University Medical Center, Herbert Irvine Comprehensive Cancer Center, New York, NY 10032.
Exact topic Proteomics and Genomics Research Cited by 1 doi:10.14302/issn.2326-0793.jpgr-13-357

How this research is being cited

The 3 articles above have been cited 8 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Metabolic Labeling, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Glycomics And Metabolism (ISSN 2572-5424).

Journal editorial board
Bassam Elgamoudi · Australia Carola Parolin · Italy Giuseppe Maurizio Campo · Italy

This page summarises published research for orientation; it is not medical or professional advice.