Research Topic · Peer-Reviewed

Sry Box

4 SRY Box 4 is a gene located on the human X chromosome that is responsible for male sexual determination. Specifically, it is involved in the early stages of embryonic development when the gonads are formed, resulting in the development of either testes or ovaries. Mutations in this gene can lead to sex reversal i…

Curated from this journal's research 📚 2 peer-reviewed articles cited Cited 18× across the literature 🔖 ISSN 2694-1198 🗓 Reviewed June 2026

Overview

4 SRY Box 4 is a gene located on the human X chromosome that is responsible for male sexual determination. Specifically, it is involved in the early stages of embryonic development when the gonads are formed, resulting in the development of either testes or ovaries. Mutations in this gene can lead to sex reversal in a male fetus, so it is an important regulator of normal development. SRY Box 4 has also been linked to fertility in males, and its expression can be used as a biomarker for testing male infertility. As a result, SRY Box 4 has been studied extensively to understand its role in sex determination and fertility.

Research published in this journal

2 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 2 articles above have been cited 18 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Sry Box, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Genetic Engineering (ISSN 2694-1198).

Journal editorial board
Gabriela Roca · Germany Khalid Al-Nedawi · Canada Giuliana Giardino · Italy

This page summarises published research for orientation; it is not medical or professional advice.