Overview
Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, serving as a protective warning system but also, when persistent, becoming a disease in its own right. It is broadly classified as nociceptive (arising from activation of peripheral nociceptors), neuropathic (arising from lesion or disease of the somatosensory nervous system), and nociplastic (arising from altered central processing), and it is further divided by duration into acute, chronic, and cancer pain. The underlying neurobiology involves peripheral transduction, spinal modulation, ascending and descending pathways, and central plasticity, including synaptic and somatic changes in regions such as the dentate gyrus and endogenous opioid signaling. Pain management is the clinical discipline devoted to its assessment and treatment, employing pharmacological agents, interventional procedures, neuromodulation, and non-pharmacological strategies. Research themes include chronic pain after thoracic surgery and transplantation, high-dose capsaicin and novel toxins for refractory pain, auricular vagus nerve stimulation and cytokine modulation, music-induced analgesia through endogenous opioids, musculoskeletal and neuralgic pain, the interface of chronic pain with mood and end-of-life attitudes, and clinical decision-support tools that integrate analgesic dosing with pain trends. The journal publishes peer-reviewed clinical, mechanistic, and translational research on pain and its multimodal management across diverse conditions and populations.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
First Lumbar Treatment of Chronic Mixed Low Back Pain with High Dose Capsaicin 8% Patch
Auricular Vagus Nerve Stimulation Improves Chronic Pain and Pain-Related Cytokine Levels: A Clinical Study
Creation of Music-Induced Analgesia in Chronic Pain Patients through Endogenous Opioid Production: A Narrative Review
Pain between Psyche and Soma in Uro-Andrology
New Pain Management Procedure after Total Knee Arthroplasty: Gonyautoxins are Safe and Effective after A Single Intra-Articular Infiltration
Neck, Shoulder and Low Back Musculoskeletal Pain in Greek Physical Education University Students: A Series of Three Cross-Sectional Studies
Perception Threshold Variations of Pain Area with Herpetic Ophthalmic Neuralgia
The Relationship of Chronic Pain to Attitudes Toward Sucide and Physician-Assisted Suicide among Latino and Non Hispanic White Elders
Combined Therapy Versus Usual Care in the Treatment of Depressed Cancer Patients with Pain
Integrating Analgesic Doses and Pain Trend Analysis: A Novel Clinical Support System
Pain Perception Modulates Synaptic and Somatic Plasticity in the Dentate Gyrus of Rats
How this research is being cited
The 12 articles above have been cited 30 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Journal of Surgical Research
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2026 · Neurology International
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2025 · Slovenian Journal of Public Health
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2025 · Journal of Psychosomatic Research
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Maja Mikša Podobnik et al. · 2025 · Slovenian Journal of Public Health
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2025 · Expert Review of Medical Devices
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2025 · Expert Review of Medical Devices
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2024 · Clinical Transplantation
A sample of recent works citing this journal's research on Pain, linking to each citing work.