Research Topic · Peer-Reviewed

Caco-2 Cells

Caco-2 Cells are a widely used cell line derived from a human colon cancer cell line, which is essential for drug absorption and toxicity testing in the pharmaceutical industry. The Caco-2 cell line is a commonly used model to study absorption, transport, and metabolism of drugs in the intestine due to its robustnes…

Curated from this journal's research 📚 2 peer-reviewed articles cited Cited 5× across the literature 🔖 ISSN 2574-4526 🗓 Reviewed June 2026

Overview

Caco-2 Cells are a widely used cell line derived from a human colon cancer cell line, which is essential for drug absorption and toxicity testing in the pharmaceutical industry. The Caco-2 cell line is a commonly used model to study absorption, transport, and metabolism of drugs in the intestine due to its robustness and its ability to form cell-to-cell tight junctions. The Caco-2 cell line has been used in the study of drug absorption, metabolism, and toxicity in a wide range of pharmaceuticals. In addition, it has been used to study physiological processes including epithelial cell-cell interactions, intestinal metabolism, intestinal permeability, and nutrient absorption. The Caco-2 cell line is a valuable tool for drug discovery and development, providing important information for the optimization of drug formulations and drug delivery systems.

Research published in this journal

2 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 2 articles above have been cited 5 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Caco-2 Cells, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Digestive Disorders And Diagnosis (ISSN 2574-4526).

Journal editorial board
Jonas P. DeMuro · United States Divey Manocha · United States Beata Kasztelan-Szczerbinska · Poland

This page summarises published research for orientation; it is not medical or professional advice.