Research Topic · Peer-Reviewed

Epidermis

The epidermis is the outermost layer of the skin, a stratified squamous epithelium that forms the body's primary barrier against water loss, mechanical insult, ultraviolet radiation, and microbial invasion. It is organized into distinct strata, the basale, spinosum, granulosum, and corneum, through which keratinocyt…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 94× across the literature 🔖 ISSN 2471-2175 🗓 Reviewed July 2026

Overview

The epidermis is the outermost layer of the skin, a stratified squamous epithelium that forms the body's primary barrier against water loss, mechanical insult, ultraviolet radiation, and microbial invasion. It is organized into distinct strata, the basale, spinosum, granulosum, and corneum, through which keratinocytes proliferate from the basal layer, differentiate as they migrate outward, and ultimately form the cornified envelope. Resident melanocytes, Langerhans cells, and Merkel cells contribute pigmentation, immune surveillance, and sensation. Epidermal homeostasis depends on tightly regulated ion transport, membrane-pump activity, and metal-ligand and lipid balance that sustain hydration and barrier integrity, and its disruption underlies inflammatory, infectious, and neoplastic skin disease. Research in this area examines transmembrane sodium and potassium traffic and Na+/K+-ATPase function in epidermal cells, criticality and synchronization of membrane-pump operation, regulatory metal-ligand homeostasis, epithelial-mesenchymal transition at the dermo-epidermal junction in neoplasia, eccrine porocarcinoma, and treatment of epidermal lesions including actinic keratosis, basal cell carcinoma, and melanoma. The journal publishes peer-reviewed studies on epidermal structure and physiology, keratinocyte biology, barrier function and ion transport, and the pathological processes affecting this outermost cutaneous layer.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2019

Transmutation of Sweat Glands - Eccrine Porocarcinoma

Bajaj AnubhaCorresponding author
MD. (Pathology) Panjab University, Department of Histopathology, A.B. Diagnostics, A-1, Ring Road , Rajouri Garden, New Delhi, 110027, India.
Exact topic Clinical and Diagnostic Pathology Cited by 3 doi:10.14302/issn.2689-5773.jcdp-19-2890
2017

Embryogenesis and Applications of Fingerprints- a review

LH AdamuCorresponding author
Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, Bayero University, Kano, Nigeria
Exact topic International Journal of Human Anatomy Cited by 21 doi:10.14302/issn.2577-2279.ijha-17-1539
2018

Modelling Development in Plant Anatomy

W. Korn RobertCorresponding author
Department of Biology, Bellarmine University, Louisville Ky. 40205, USA
Exact topic Advances in Plant Biology Cited by 2 doi:10.14302/issn.2638-4469.japb-18-2127
2016

Does a Controlled Diet Improve Cellulite?

S Yarak,Corresponding author
Universidade Federal de São Paulo, Dermatology Department. 
Exact topic International Journal of Nutrition Cited by 6 doi:10.14302/issn.2379-7835.ijn-16-986

How this research is being cited

The 12 articles above have been cited 94 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Epidermis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Dermatologic Research And Therapy (ISSN 2471-2175).

Journal editorial board
Wenbin Tan · United States Anand Rotte · United States David Fisher · United States

This page summarises published research for orientation; it is not medical or professional advice.