Overview
Treatment of depression encompasses the therapeutic approaches used to relieve depressive symptoms, restore function, and prevent relapse in mood disorders. Management is typically stepped and individualized according to severity, comorbidity, and patient preference, and combines pharmacotherapy, structured psychotherapy, lifestyle and behavioral measures, and, for resistant or severe illness, additional biological interventions. Antidepressant medications act on monoaminergic and related neurotransmitter systems, while psychotherapies such as cognitive-behavioral and rumination-focused therapy modify maladaptive thoughts and behaviors; ongoing assessment guides adjustment and continuation. Treatment must also address depression as it occurs alongside other conditions, including dementia, cognitive impairment, chronic illness, and cancer, where presentation and response may differ. Research relevant to this area examines the relationship between depression and dementia, depression and social support in persons with disability, rumination-focused cognitive-behavioral therapy, severity of hopelessness in depressed inpatients, executive dysfunction in depression, ketamine-based treatment of major depressive disorder, behavior management for depression in dementia, combined therapy for depressed patients with pain, biofeedback interventions, and music therapy in health services. The journal publishes peer-reviewed studies on the pharmacological, psychotherapeutic, behavioral, and integrative treatment of depression, including treatment response, management of comorbid and treatment-resistant presentations, and interventions across clinical and community settings.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
How this research is being cited
The 12 articles above have been cited 39 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · BMC Psychology
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2025 · Neuropsychiatric Disease and Treatment
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2025 · Journal of Psychosomatic Research
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2025 · Neuropsychiatric Disease and Treatment
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2023 · Comprehensive Psychiatry
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M. Gerber et al. · 2023 · Journal of Clinical Medicine
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2023 · Journal of Clinical Medicine
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2023 · Advanced Biology
A sample of recent works citing this journal's research on Treatment of Depression, linking to each citing work.