Primary Cells

Primary cells are a type of cell culture that is derived directly from live tissues or organs. These cells retain their original characteristics and can be used for a range of scientific investigations, including drug development, disease modeling, and basic research. One major advantage of primary cells is that they offer a more realistic representation of in vivo biological processes than immortalized cell lines, which have undergone genetic modifications that can alter their behavior compared to their normal counterparts. In addition, primary cells can be used to test the efficacy and safety of potential drugs, as they can more accurately predict the effects of drug candidates and their interactions with human cells. There are many types of primary cells, including fibroblasts, epithelial cells, neurons, and stem cells, among others, each with their own unique characteristics, applications, and challenges. For example, isolation and culture of primary cells can be challenging due to their limited lifespan and specialized culture requirements. Despite these challenges, primary cells are an important tool for scientific research, as they allow scientists to study the complex interactions between cells, their environment, and potential drugs or therapies. As technology continues to advance, new methods of culturing and characterizing primary cells will undoubtedly emerge, providing even more powerful tools for biomedical research.

← Journal of Current Scientific Research

Related Articles

54 article(s) found
Optimization and ZSPORE Analysis of Affinity Purification Coupled with Tandem Mass Spectrometry in Mammalian Cells
Full-text HTML Download PDF Download XML
Substrate Stiffness Influences the Time Dependence of CTGF Protein Expression in Müller Cells
Full-text HTML Download PDF Download XML
Antioxidant Protection of Donor Packed Red Blood Cells using Mexidol
Full-text HTML Download PDF Download XML
What Do Primary Care Prediabetes Patients Need? A Baseline Assessment of Patients Engaging in A Technology-Enhanced Lifestyle Intervention.
Full-text HTML Download PDF Download XML
Evaluating the Efficacy of Gene Silencing in Dopaminergic Neuronal Cells In-Vitro using Gold Nanorods (GNR) with Different Surface Properties Complexed to DARPP-32 siRNA.
Full-text HTML Download PDF Download XML
Factors that Influence Fenofibrate Effects on Cancer Cells
Full-text HTML Download PDF Download XML
Mechanisms Associated with Acquisition of Resistance to Butyrate-Induced Apoptosis in Colorectal Cancer Cells Using Gene Expression Analysis
Full-text HTML Download PDF Download XML
Evaluating the Role and Efficacy of Plerixafor in Rescue Mobilization of Autologous Peripheral Blood Stem Cells
Full-text HTML Download PDF Download XML
Laryngeal Tissue Engineering using Rabbit Adipose Derived Stem Cells in Fibrin: A Pre-Clinical Model
Full-text HTML Download PDF Download XML
Overexpression of Prostate Apoptosis Response Protein-4 In Colon Cancer Cells Can Inhibit Metastasis by Upregulating E-cadherin Expression
Full-text HTML Download PDF Download XML
Evaluating Circadian Oscillators in Cancer Stem Cells
Full-text HTML Download PDF Download XML
Primary Abdominal Wall Reinforcement with Synthetic Mesh Following Harvesting of Vertical Rectus Abdominis Myocutaneous Flaps in Multivisceral Pelvic Resections
Full-text HTML Download PDF Download XML
Radical-Scavenging and Anti-Oxidative Activities of TBN in Cell-Free System and Murine H9c2 Cardiomyoblast Cells
Full-text HTML Download PDF Download XML
Thyroid Transcription Factor-1 Activity is Required for the Proliferation of Human Thyroid Cancer Cells 8505C
Full-text HTML Download PDF Download XML
Cholesterol-Conjugated siRNA Accumulates in the Different Hematopoietic and Lymphoid Cells.
Full-text HTML Download PDF Download XML
Ciliary Neurotrophic Factor Activated Signaling Pathways in Retinal Müller Cells
Full-text HTML Download PDF Download XML
Mental Health Promotion for the ‘In-Betweeners’: The Rationale and Effectiveness of Community-Based Mentoring and Coaching Schemes for Primary School-Aged Children.
Full-text HTML Download PDF Download XML
Outcome in Patients with Spontaneous Primary Intracranial Hemorrhage who underwent Craniotomy Affiliation
Full-text HTML Download PDF Download XML
Cytoplasmic Retention of CDC6 Induces Premature Senescence in Immortalized Cells and Suppresses Tumor Formation in Mice
Full-text HTML Download PDF Download XML
Primary Malignant Melanoma Of The Parotid Gland Combined 18F-FDGPET/CT And Immunochemical Diagnosis with Literature Review
Full-text HTML Download PDF Download XML
Human Umbilical Cord-Derived Mesenchymal Stem Cells as a Source of Odontoblasts: a GMP-compliant Approach
Full-text HTML Download PDF Download XML
Dual Effects of Neuroprotection and Neurotoxicity by General Anesthetics on Neural Stem Cells: Role of Autophagy
Full-text HTML Download PDF Download XML
Expression of Estrogen Receptor β in Hypothalamic Stem Cells
Full-text HTML Download PDF Download XML
Nanotechnology Meets Immunotherapy: CAR-T Cells Technology and Beyond
Full-text HTML Download PDF Download XML
Some Aspects of Regulatory Criteria for Metal-ligand Homeostasis in Epidermal Cells
Full-text HTML Download PDF Download XML
Perspectives on Sub–Nanometer Level of Electronic Structure of the Synchrotron with Mendelevium Nanoparticles for Elimination of Human Cancer Cells, Tissues and Tumors Treatment Using Mathematica 12.0
Full-text HTML Download PDF Download XML
Cancer Stem Cells: A Cause or A Consequence of Field Cancerization
Full-text HTML Download PDF Download XML
Assessment of Energy of Consciousness Healing on Cell Growth of Plant Stem Cells Callus Culture
Full-text HTML Download PDF Download XML
Membrane Pump Operation Synchronicity (Criticality) in Epidermal Cells: The Possibility of Quantifying the Level of Synchronization
Full-text HTML Download PDF Download XML
Application of Nanotechnology for the Preservation of Red Blood Cells
Full-text HTML Download PDF Download XML
Epilepsy: Knowledge and Attitudes of Primary School Teachers in the City of Bouake/Ivory Coast
Full-text HTML Download PDF Download XML
Perioperative Period is a Critical Gap for Minimal Residual Cancer Cells Progression and Therapy: Biological and Molecular Based Evidences
Full-text HTML Download PDF Download XML
Antioxidative Potential of Consciousness Energy Healing Treatment on HepG2 Cells and DMEM after Oxidative Stress Induced by Hydrogen Peroxide
Full-text HTML Download PDF Download XML
Evaluation of Blood Ordering Practice for Packed Red Blood Cells in A Tertiary Care Hospital
Full-text HTML Download PDF Download XML
Effect of Bone Marrow and Adipose Mesenchymal Stem Cells on Rat Intestinal Injury Induced by Methotrexate
Full-text HTML Download PDF Download XML
Selective Cytotoxicity of Damsin Derivatives in Breast Cancer Cells
Full-text HTML Download PDF Download XML
The Location and Diameter of the Primary Maxillary Sinus Ostium in Malaysians: A Cone-Beam Computerized Tomography Study
Full-text HTML Download PDF Download XML
Differential of Antioxidant Ability, CD4+T Cells Count and Viral Load in HIV Infected Patients on cART in Yaounde, Cameroon
Full-text HTML Download PDF Download XML
Investigation of Neoplastic Cells in the Bone Marrow of Female Dogs with Mammary Gland Tumors
Full-text HTML Download PDF Download XML
SARS-CoV-2 affected cells Pathogeny and Therapy
Full-text HTML Download PDF Download XML
Process Evaluation of Auditable Pharmaceutical Transaction Service in Seka primary Hospital, Jimma Zone, South West Ethiopia
Full-text HTML Download PDF Download XML
Therapeutic Potential of Autologous Adipose Derived Mesenchymal Stem Cells in Human POI and Ovarian Aging
Full-text HTML Download PDF Download XML
Elasticity Profile of Skin, Neuronal, Cardiac, and Skeletal Muscle Cells after Treatment with the Biofield Energy Healing-Based Proprietary Test Formulation
Full-text HTML Download PDF Download XML
Identify the Effects of Ultra Weak Light on Alphacoronavirus and Vero Cells
Full-text HTML Download PDF Download XML
Evolution of the Solid Human Tumor Cells Properties in Various Experimental Systems in Vitro
Full-text HTML Download PDF Download XML
Primary Breast Sarcoma
Full-text HTML Download PDF Download XML
Barriers and Opportunities to Improve the Implementation of Patient Screening and Linkage to Pre-Exposure Prophylaxis in Primary Care
Full-text HTML Download PDF Download XML
Challenger Treatment of Various Cancers with T Cells Engineering
Full-text HTML Download PDF Download XML
Primary Leiomyosarcoma of the Thyroid; a Case Report and a Review of Recent Literature
Full-text HTML Download PDF Download XML
Health-Related Quality of Life Perception Among Older Persons with Non-Communicable Diseases in Primary Healthcare Facilities: A Qualitative Inquiry
Full-text HTML Download PDF Download XML
Primary Healthcare Services and Health-Related Quality of Life of Older Persons with Non-Communicable Diseases: A Narrative Literature Review
Full-text HTML Download PDF Download XML
Primary Membranous Nephropathy Flare After COVID-19 Vaccination
Full-text HTML Download PDF Download XML
Burden of Unintentional Childhood Injuries in Pre-School Children (2-6yrs) and Knowledge of Primary Caregivers on Early Management: A Descriptive Observational Study in Urban Slums of Bhubaneswar, Odisha
Full-text HTML Download PDF Download XML
Prevalence and Risk Factors of Intestinal Parasitic Helminths among Primary School Children in Oru West Lga, Imo State, Nigeria
Full-text HTML Download PDF Download XML