Research Topic · Peer-Reviewed

Liquid Chromatography-tandem Mass Spectrometry

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a powerful tool used in current scientific research. It is a technique that combines the separation capabilities of liquid chromatography with the detection and identification capabilities of mass spectrometry. In LC-MS/MS, a sample containing different m…

Curated from this journal's research 📚 5 peer-reviewed articles cited Cited 95× across the literature 🔖 ISSN 2766-8681 🗓 Reviewed June 2026

Overview

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a powerful tool used in current scientific research. It is a technique that combines the separation capabilities of liquid chromatography with the detection and identification capabilities of mass spectrometry. In LC-MS/MS, a sample containing different molecules is passed through a chromatographic column, which separates the molecules based on their physicochemical properties. The separated molecules are then ionized and the resulting ions are analyzed by a mass spectrometer. The mass spectrometer detects the mass-to-charge ratio (m/z) of the ions and generates a mass spectrum. LC-MS/MS has revolutionized the field of proteomics, metabolomics, and drug discovery. It can be used to identify and quantify a wide range of compounds, such as proteins, peptides, lipids, nucleic acids, and small molecules. It is also a powerful tool for biomarker discovery, which is important for developing diagnostic and prognostic tests for different diseases. LC-MS/MS is a highly sensitive technique, allowing the detection and quantification of a wide range of compounds even at low concentrations. Moreover, it is a fast and efficient technique, capable of analyzing thousands of samples within a short period of time. In conclusion, LC-MS/MS is a powerful technique that has revolutionized the field of bioanalytical chemistry. It has numerous applications in different fields, including clinical diagnosis, drug discovery, and environmental analysis. Its versatility, sensitivity, and efficiency make it a go-to tool for researchers worldwide.

Research published in this journal

5 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 5 articles above have been cited 95 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Liquid Chromatography-tandem Mass Spectrometry, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Current Scientific Research (ISSN 2766-8681).

Journal editorial board
Eva Volna · Czech Republic Shailendra Dwivedi · United States Saeid Jafarzadeh-Ghoushchi · Iran

This page summarises published research for orientation; it is not medical or professional advice.