Research Topic · Peer-Reviewed

Hereditary Nonpolyposis Colorectal Cancer

Hereditary nonpolyposis colorectal cancer (HNPCC) is an inherited form of colorectal cancer that can put individuals at a higher risk of developing the disease. HNPCC is caused by mutations in certain genes that control DNA repair, which results in an increased susceptibility to cancer-causing factors. This form of …

Curated from this journal's research 📚 1 peer-reviewed article cited 🔖 ISSN 2471-7061 🗓 Reviewed June 2026

Overview

Hereditary nonpolyposis colorectal cancer (HNPCC) is an inherited form of colorectal cancer that can put individuals at a higher risk of developing the disease. HNPCC is caused by mutations in certain genes that control DNA repair, which results in an increased susceptibility to cancer-causing factors. This form of colorectal cancer is associated with increased rates of cancer in the colon, rectum, and other parts of the body, such as the endometrium, stomach, ovary, and small intestine. People with HNPCC typically have a family history of colorectal cancer and may also have a personal history of colorectal cancer. Treatment for HNPCC typically includes preventive measures, such as avoiding smoking and reducing alcohol consumption, as well as genetic counseling and genetic testing. In addition, regular colorectal cancer screening is recommended to catch any developing malignancies in its earliest stages.

Research published in this journal

1 peer-reviewed article, ranked by relevance. Each links to its DOI.

Editorial oversight

Curated from peer-reviewed research published in Colon And Rectal Cancer (ISSN 2471-7061).

Journal editorial board
Frank A. Frizelle · New Zealand Gennaro Galizia · Italy Tamotsu Tsukahara · Japan

This page summarises published research for orientation; it is not medical or professional advice.