Caco-2 Cells
Caco-2 cells are a type of human colonic epithelial cell line used in research for drug absorption, metabolism, and transport studies. Their use gives researchers insight into the implications of drug properties and their availability for clinical use. These cells are important tools for evaluation of intestinal absorption, toxicity and drug efficacy, as they can replicate many of the biological functions of human gut epithelium, including metabolism and transport. Caco-2 cells can also be used to predict drug pharmacokinetics and interaction with target tissues, including absorption, distribution, metabolism, and excretion. Caco-2 cells are widely used to assess the potential safety and efficacy of new drug candidates, including pharmaceuticals and natural products, before they are tested in clinical trials.
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