Highly active antiretroviral therapy (HAART) is the combined use of three or more antiretroviral drugs to treat infection with the human immunodeficiency virus (HIV). By acting on different stages of the viral life cycle simultaneously, the combination suppresses viral replication more effectively than single agents…
Highly active antiretroviral therapy (HAART) is the combined use of three or more antiretroviral drugs to treat infection with the human immunodeficiency virus (HIV). By acting on different stages of the viral life cycle simultaneously, the combination suppresses viral replication more effectively than single agents and reduces the likelihood of drug resistance. Sustained HAART lowers the amount of virus in the body to undetectable levels, allows the immune system to recover, prevents progression to AIDS, and substantially reduces the risk of transmission, transforming HIV infection into a manageable chronic condition. Effective therapy depends on adherence and on monitoring for adverse drug reactions, which can complicate long-term treatment. Research relevant to this topic in Clinical Research in HIV/AIDS and Prevention includes studies on patterns of use of HAART regimens and associated adverse drug reactions in HIV-positive patients in India, evaluation of the direct cost of those adverse reactions, the effect of nucleoside and nucleotide reverse transcriptase inhibitors on telomerase function and aging, and a case report of rhabdomyolysis following the addition of raltegravir. This page gathers peer-reviewed, open-access research relevant to the topic.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 58 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Highly Active Antiretroviral Therapy, linking to each citing work.