Molecular Genetics Pathology

Molecular Genetics Pathology is the study of genetic alterations at the level of DNA, RNA, and proteins in order to understand the etiology of diseases. It is of particular significance in the diagnosis and treatment of various genetic disorders, and also for predicting responses to drugs. Molecular Genetics Pathology is employed for the diagnosis and prognosis of an increasing number of diseases such as cancer, cystic fibrosis, Huntington’s disease and many more. In addition, it is also used in forensic medicine and newborn screening. The use of molecular tools in genetic testing has revolutionized the field and enabled the determination of both disease-causing mutations and phenotypes in a fast, cost-effective and accurate manner.

← Journal of Clinical and Diagnostic Pathology

Related Articles

45 article(s) found

Molecular Cytogenetic Investigations in a Novel Chromosomal Abnormality of t(10;15)(q22;q22) in a Pediatric Precursor-B-Acute Lymphoblastic Leukemia Patient

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A Review of the Histologic, Genetic and Molecular Characteristics of Meningioma Pathogenesis and Progression

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Understanding Ubl-Rpn1 Intermolecular Interaction

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Epigenetics and Nutrition

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Subjective and Objective Actigraphic Sleep Monitoring and Psychopathology in a Clinical Sample of Patients with Night Eating Syndrome, with and Without Binge Eating Behaviors

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Newly-Detected Solitary Bony Lytic/Sclerotic Lesion with Soft Tissue Mass in a Previously Treated Case of High-Risk Medulloblastoma: Importance of Contemporary Pathology Techniques to Differentiate Second Malignant Neoplasm from Extra-Neuraxial Metastasis 

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Investigations of Molecular Evolutionary Mechanisms in Partially Sequenced Heat Shock Protein70 Homologue-Coding Gene of Olive Leaf Yellowing-Associated Virus Isolates from Tunisia

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Molecular Structure and Vibrational Analysis of 2-(4-methoxyphenyl)-2, 3-Dihydro-1H-Perimidine using Density Functional Theory

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Psychopathology of Brain Frontal Lobe Tumors : When the Neurosurgery Meets Psychiatry

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Regulation of Expression of Reactive Oxygen Intermediates During Plasmodium Infection to Reduce Immunopathology Provides a Possible Antioxidant Adjuvant to Enhance Anti-Malarial Drug Therapy

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Molecular Spectroscopy and Molecular Docking Studies on (E)-1-(4-Bromobenzylidene) Thiourea

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Scientific and Technological Interventions for Attaining Precision in Plant Genetics and Breeding

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Molecular and Cell Biological Considerations in the Initiation and Development of Sporadic Non-Hereditary Solid Cancers  

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Perioperative Period is a Critical Gap for Minimal Residual Cancer Cells Progression and Therapy: Biological and Molecular Based Evidences

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Molecular Biomarkers: A Brief Review

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Molecular Survey on Symbiodinium of Some Scleractinean Coral Spp. and a Fire Coral sp. along the Red Sea of Egypt

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Molecular Composition of and Potential Health Benefits Offered by Natural East African Virgin Sunflower Oil Products: A 400 MHz 1H NMR Analysis Study

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Developing Cellular & Molecular Biomarkers for Anti-Inflammatory Activities of Probiotic Bacteria in Fermented Foods

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Construction of Virtual Neuron and Consolidation of Sleep and Memory Process– A Molecular Docking and Biomathematical Approach

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Neuroscience Theories, Hypothesis and Approaches to ASD Physiopathology. A Review

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Molecular and Metabolic Pathogenesis of Familial Combined Hyperlipidemia and Association with Metabolic Syndrome

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Natural Selection in a Population is a Problem of Nonlinear Genetics

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The Intersection of Cultural Characteristics and Genetics on the Prevalence of Delayed Sleep Phase Syndrome in Brazilian and Japanese Adults

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Molecular Study of Hepcidin HAMP (-582A/G) Gene Polymorphisms and Measurement of Serum Hepcidin Level among Sudanese Patients with Anemia of Chronic Kidney Disease

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Molecular Analysis of 6-pyruvoyltetrahydropterin Synthase Gene in Atypical Phenylketonuric Egyptian Patients

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Aerobic Plate Count of Contaminants and Molecular Characterization of Eschereichia Coli in Raw Chicken Meat in Ismailia, Egypt

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Clinical Gastroenterological Manifestations as Criteria for the Pathology and Effectiveness of Surgical Correction of Reflux Disease of the Digestive System

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Molecular Evolutionary Characteristics of the 2019 Novel Coronavirus (SARS-CoV-2) Contracted by Tunisian Citizens : Comparison and Relationship to Other Human and Animal Coronaviruses Based on Spike Glycoprotein-Coding Gene Sequences Analysis

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Molecular Evolution of the Novel Coronavirus SARS-CoV-2

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Use of the Remaining Sample from the Panbio COVID-19 Antigen Rapid Test Device for the Molecular Screening of the SARS-CoV-2 Variant of Concern B.1.1.7

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The Metabolic and Neurochemical Etiopathology of Passive Exposition to Alcohol Consumers

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Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryo during Organogenesis and their Role as Epigenetics Regulators able to Reverse Neurosensory Hearing Loss

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Tay-Sachs Disease: From Molecular Characterization to Ethical Quandaries and the Possibility of Genetic Medicine

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Molecular Detection of Mycoplasma Gallisepticum and Mycoplasma Synoviae Infection in Poultry

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Molecular Confirmation of Staphylococci Strain’s Identification Isolated in the Hospital and University Center of Brazzaville, Republic of Congo

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CERN Large Hadron Collider (LHC) Radiation Source for Magnetic Resonance Biospectroscopy in Metabolic and Molecular Imaging and Diagnosis of Cancer

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Molecular Diagnosis in Clinical Management and Diagnosis of Thyroid Cancer

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Rbm45 Phylogenetics, Protein Domain Conservation, and Gene Architecture in Clade Metazoa

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Quantum Approach to Allergic Pathology

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The Heart Physiology in Fertile Female and The Heart Pathophysiology in Post Menopausal Female. The Contribution of Molecular Biology, Maintaining Cardiac Hemodinamy and Electrophysiology

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RBM45: Molecular, Cellular, and Evolutionary Biology

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Intramuscular Fat Deposition and Osteoarthritis Pathology: A Possible Overlooked Pathogenic Correlate?

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Molecular Control of Human Embryonic Development: A Comprehensive Study

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Persistent Neovascular Exudation in Patients with Exudative Age-Related Macular Degeneration who have Choroid Imaging Biomarkers of Non-Neovascular Choroidal Pathology: Simultaneous Choroidal Hyperpermeability and Angiogenesis

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Molecular Approaches for Assessing Some Iranian Freshwater Fish Species

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