Isothermal Titration Calorimetry

Isothermal Titration Calorimetry (ITC) is a technique used to measure the thermodynamic properties of interacting molecules. This technique utilizes heat absorption or release when two or more molecules are brought together, to determine how strongly they interact. This information is used to study protein-ligand interactions, enzymatic activity, and the stability of complexes. Due to its high sensitivity and accuracy, ITC is increasingly becoming a powerful tool for research in areas such as drug discovery and development.