Thin-Layer Chromatography

Overview

Thin-layer chromatography is an analytical technique that separates chemical compounds by distributing them between a stationary phase coated on a flat surface and a mobile solvent phase, enabling identification and quantification of components in complex mixtures. Research published in Advances in Nanotechnology demonstrates applications of this method across pharmaceutical quality control, natural product analysis, and biochemical investigation. Studies have employed thin-layer chromatography to profile phytochemical constituents in plant extracts, including compounds from Senna occidentalis, Tinospora cordifolia, Jatropha tanjorensis, and Acanthus montanus, supporting both traditional medicine research and bioactivity screening. The technique has proven valuable for detecting adulterants in dietary supplements marketed for sexual enhancement and for separating benzoic esters in pharmaceutical formulations. Additional applications include monitoring transesterification reactions in biodiesel production, analyzing lipid components in neurological tissue fractions, characterizing nucleoside analogues during synthetic chemistry workflows, and assessing membrane lipid alterations following toxicant exposure. These diverse implementations underscore thin-layer chromatography's continued relevance as an accessible, cost-effective separation method for preliminary analysis, reaction monitoring, and quality assessment across pharmaceutical development, natural products chemistry, and biochemical research.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 77 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

• Deciphering the detailed crystallographic structure of biologically synthesized nano-silver: Antioxidant potential, antimicrobial efficacy and anticancer properties against HepG2 cancer cell line with accentuation to apoptosis and ROS generation
  2026 · Journal of Molecular Structure
• Green-Synthesized titanium dioxide Nanoparticle–Modified glass ionomer cement: in vitro and in Silico assessment of Mechanical, Physical, and safety properties performance
  2026 · Scientific Reports
• Phytofabricated Silver Nanoparticles from Origanum majorana: Anti-Pathogenic Activity and Biocompatibility Evaluation
  2026 · Microbial Pathogenesis
• Antagonistic Bacterial Endophytes from Gingers and their Metabolite Mediated Interactions Against Pythium Soft Rot
  2026 · Current Microbiology
• Green Synthesis of Silver Nanoparticles Using Cynoglossum creticum Leaf Extract: Eco-Friendly Approach for Antibacterial, Antioxidant, and Sensing Applications
  2025 · Applied Biochemistry and Biotechnology
• Insights into synergistic antibacterial effects, antioxidant potential, and anticancer activities of green-synthesized silver nanoparticles from Odontosoria chinensis leaves
  2025 · Next Nanotechnology
• Antioxidant and ameliorative effects of selected Nigerian plants on hormonal imbalance associated with dysmenorrhea in albino rats
  2025 · Frontiers in Nutrition
• The Multifaceted Chemistry of Chili Peppers: A Biodiversity Treasure for Nutrition and Biomedicine
  2025 · Chemistry & Biodiversity

A sample of recent works citing this journal's research on Thin-Layer Chromatography, linking to each citing work.

This page summarises published research for orientation; it is not medical or professional advice.

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