Glycerolization is a pharmaceutical and chemical process in which glycerol, also known as glycerin, is incorporated into a substance or formulation, either to dissolve or stabilize an active ingredient or to modify the physical properties of a product. In pharmaceutical science and technology, glycerol is widely val…
Glycerolization is a pharmaceutical and chemical process in which glycerol, also known as glycerin, is incorporated into a substance or formulation, either to dissolve or stabilize an active ingredient or to modify the physical properties of a product. In pharmaceutical science and technology, glycerol is widely valued as a solvent, humectant, sweetener, and stabilizer because it is non-toxic, miscible with water, and capable of improving the solubility, palatability, and shelf stability of many preparations. Glycerolization is therefore used in producing liquid dosage forms, syrups, and other preparations of water-soluble drugs, where glycerol helps adjust viscosity, protect against microbial growth, and improve mouthfeel and consistency. The same principle underlies the use of glycerol to preserve biological materials and tissues, where it acts as a protective agent against damage during storage. Within Advanced Pharmaceutical Science And Technology, glycerolization reflects the broader role of excipients and formulation chemistry in turning an active compound into a safe, stable, and usable medicine. Understanding how solvents and carriers such as glycerol influence drug delivery and stability is fundamental to developing effective dosage forms. This page gathers definitional and scope context relevant to glycerolization within pharmaceutical science.
1 peer-reviewed article, ranked by relevance. Each links to its DOI.