Drug Efficacy Evaluation

Drug efficacy evaluation is a fundamental aspect of pharmaceutical science and technology. It involves the assessment of a drug's ability to achieve its intended therapeutic goal in a safe and efficient manner. It is of utmost importance to ensure that drugs are effective, as patients rely on them to alleviate symptoms and cure illnesses. Drug efficacy evaluation involves testing the drug in pre-clinical and clinical trials. The pre-clinical trials test the drug's safety and efficacy in the laboratory, using animals and cell cultures. This phase of the evaluation helps to determine the optimal dosage, toxicity, and potential side effects of the drug. Once the drug passes the pre-clinical trials, it moves on to the clinical trials, where it is tested on humans. Clinical trials involve testing the drug in different phases, and each phase involves a larger sample size of individuals. The first phase tests the safety and dosage of the drug, while the second phase tests its efficacy. The third phase tests whether the drug is better than existing medications or treatment options. If the drug is approved, it is launched in the market, and post-marketing surveillance is conducted to detect any potential adverse effects. In conclusion, drug efficacy evaluation is the backbone of pharmaceutical science and technology, ensuring that drugs are safe and effective for patients. Without it, drugs could cause more harm than good. Therefore, pharmaceutical companies, regulatory bodies and clinicians must work together to ensure that drugs are thoroughly evaluated and monitored throughout their life cycle.

← Journal of Advanced Pharmaceutical Science And Technology

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135 article(s) found
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Evaluation of Direct Cost of Adverse Drug Reactions to Highly Active Antiretroviral Therapy in Indian Human Immunodeficiency Virus Positive Patients
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Pattern of Use of Highly Active Antiretroviral Therapy Regimens and Pattern of Occurrence of Adverse Drug Reactions in an Indian Human Immunodeficiency Virus Positive Patients
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Evaluation of the Effect of Consciousness Energy Healing Treatment on the Physicochemical and Thermal Properties of Selenium
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Evaluation of SterculiaUrens Gum as Novel Carrier for Oral Colon Targeted Drug Delivery System
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Evaluation of Recruitment Approaches for the HPTN 052 Clinical Trial of HIV Serodiscordant Couples in Rural Western Kenya
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Evaluating the Efficacy of Gene Silencing in Dopaminergic Neuronal Cells In-Vitro using Gold Nanorods (GNR) with Different Surface Properties Complexed to DARPP-32 siRNA.
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Double-Blind Randomized Trial on the Efficacy in a Short-Time Follow-Up of the “Quick Liberatory Rotation” Maneuver in Treating Posterior Canal BPPV
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Current Status of Nonsteroidal Anti-Inflammatory Drugs in Colorectal Cancer Prevention
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Evaluating the Role and Efficacy of Plerixafor in Rescue Mobilization of Autologous Peripheral Blood Stem Cells
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Medullary Thyroid Cancer: Is the Adequacy of Pre-Operative Evaluation Influenced by Training Background?
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Efficacy of Focal Photocoagulation to Maintain or Achieve Best Corrected Visual Acuity ≥20/40, in Eyes with Diabetic Macular Edema
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Evaluation of the Impact of Clinical, Functional and Social Factors on the Readmission of Patients with Pluripathologies
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Evaluation of Crest Guideline Validity for Diagnosis of Non-Facial Cellulites
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Reasons for the Low Male Involvement in Routine Child Immunization in Hoima District Uganda using the Attitude, Social Influence and Self Efficacy Model
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A Comparative Evaluation of the Role of Cone Beam Computed Tomography (CBCT) Imaging and Orthopantomography (OPG) in Sinus Augmentation Procedures: An Original Study
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Evaluation of Household Radiation Exposure and Safety after Ambulatory Radioiodine Ablation Therapy
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Efficacy of Calcium Phosphosilicate (CPS) Putty As Alloplastic Bioactive Graft Material in Sinus Augmentation Procedures: An Original Study
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Synthesis and Assessment of a New Tetrahydrogeraniol Derivative as Penetration Enhancer for Transdermal Drug Delivery
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A Successful Vancomycin Treatment of Multidrug-Resistant MRSA-Associated Canine Pyoderma
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Trends and inducing factors for illicit drug use in Grenada: Epoch 2001 – 2009.
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Efficacy of a Hypocaloric Mediterranean Diet in Overweight Patients: Factors Predictive of Completion
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Evaluation of Vitamin D Deficiency in Patients with Chronic Liver Disease and Its Clinical Significance
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Evaluation of a Stroke Protocol Using Computed Tomography Angiography for the Evaluation of Acute Ischemic Stroke Patients
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Novel N-Pyrrolylcarboxylic Acid Derivative as a Potential New Analgesic and Anti-Inflammatory Drug
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Regulation of Expression of Reactive Oxygen Intermediates During Plasmodium Infection to Reduce Immunopathology Provides a Possible Antioxidant Adjuvant to Enhance Anti-Malarial Drug Therapy
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Identification of insulin-sensitive obese vs. insulin resistant obese postmenopausal women: Evaluation of surrogate indices of insulin sensitivity.
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P16/INK4a and KI-67 Evaluation of Intraepithelial and Benign Cervical Lesions at the University College Hospital, Ibadan - A Retrospective Immunohistochemically Study
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This Isn’t Just a Phantom, Menopause, But You Can Vent Your Feelings - Qualitative Evaluation of Evidence Based Health Information (EBHI) Material
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Total Proteins, β- and γ-globulins as efficacy therapy response indicators in dogs infected with Leishmania infantum – a Review
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Evaluation of Hexane Content in Edible Vegetable Oils Consumed in Iran
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Evaluation of an External Quality Assessment Program for HIV Testing in Tigray North Ethiopia 2016
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RETRACTED: Efficacy of BCG Vaccine and Role of Non Specific Sensitivity Due to Atypical Mycobacteria
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Efficacy of The Immunotargeting Therapeutic Antibody Trastuzumab in HER2-Positive Advanced Gastric Cancer: A Meta-Analysis
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Profile of Similarity of Electron Withdrawing Structure Towards Analgesic-Anti-Inflammatory Activity of The Novel Isatin Analogue: Design and Implementation of Phase I Drug Discovery
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The Efficacy of Behavior Management for Depression in Dementia Patients: A Systematic Review and Meta-Analysis
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Evaluation of Bacterial Population in the Saliva of Drug Addicts
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Evaluation of Some Sugar Beet Genotypes Under Drought Stress Based on Selection Indices
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The Development and Evaluation of A Multiplex Real-Time PCR Assay for the Detection of ESBL Genes in Urinary Tract Infections
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Drug Design Progress of In silico, In vitro and In vivo Researches
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Evaluation of Co-morbidities among Different Chronic Obstructive Pulmonary Disease Phenotypes
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Safety, Tolerability, Efficacy and Logistics of Administration of Three Types of Therapeutic Feeds to Children with Severe Acute Malnutrition (SAM)
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Acute and Subacute Toxicity Evaluation of the Stem Bark Aqueous Extract of Harungana Madagascariensis in Rodents
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Clinical Evaluation of Significance of 25(Oh)D Levels in Patients with Organophosphorus Poisoning
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Causative Factors behind an Efficacious Teacher: Evaluating Teacher Efficacy
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Evaluation of Blood Ordering Practice for Packed Red Blood Cells in A Tertiary Care Hospital
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Drug Abuse among Street Children
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Efficacy and Safety of Lycoprozen®, a Novel Tomato-Based Food Supplement in Patients with Benign Prostatic Hyperplasia
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Statistical Taguchi Optimization for Preparation and Adhesion Evaluation of Epoxy Insulator to the Surface of Double Base Propellant Grain
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The Pineal Hypothesis for Drug Dependence
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Evaluation of Serum Vitamin D Levels in Foster's Children Care Center
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Evaluation of the Effects of Health Impact Assessment (Hia) Practice in Monteregie
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Efficacy of DHA and EPA on Serum Triglyceride Levels of Healthy Participants: Systematic Review
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Consciousness Energy Healing Treatment: Spectroscopic and Calorimetric Evaluation of the Biofield Energy Treated Hydroxypropyl β-Cyclodextrin
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Why New Drugs, Treatments, and Medical Devices Still Needs to be Tested Clinically Before Making it Available in the Market?
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High-Resolution SD-OCT and EDI-OCT in the Evaluation and Management of Multifocal Serpigenoed Choroditis
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Efficacy of Commercial Symbiotic Bio-Fertilizer Consortium for Mitigating the Olive Quick Decline Syndrome (OQDS)
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Successful Cascade of Care and Cure HCV in 5382 Drugs Users: How Increase HCV Treatment by Outreach Care, Since Screening to Treatment
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Characterization of rpoB Gene Mutations Associated with Rifampicin Resistance in Multidrug Resistant Tuberculosis Patients Co-infected with HIV from Southern India.
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In VivoEvaluation of the Protective Capacity of Different Gloves Against Hair Dyes
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Evaluation of Anti-Aging Activity of the Biofield Energy Treated Novel Test Formulation Using SIRT1 and Telomerase Activity in in Vitro Model
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Evaluation of Job Satisfaction and Job Related Stress Among Community Pharmacists in North Khartoum and its Impact on Providing Pharmaceutical Care Services
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Evaluation of the Impact of Consciousness Energy Healing Treatment on the Isotopic Abundance Ratios (PM+1/PM and PM+2/PM) of Ofloxacin
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Chondroplasty Efficacy of Bone Matrix
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Evaluation of the Relationship Between Advanced Oxidation end Products and Inflammatory Markers in Maintenance Hemodialysis Patients
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Evaluations of phylogenetic proximity in a group of 67 dogs with osteosarcoma: a pilot study
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Evaluation of cardiorespiratory parameters in dogs undergoing laparoscopic versus open gonadectomy with spontaneous ventilation anaesthesia: a pilot study
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Pharmacodynamic Modeling of Sunscreens: New Efficacy Evaluation, Risks of Sunburn and Melanoma and Very Low to Very High Sun Protection Factor
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Therapeutic Evaluation of Neemazal® Against Experimental Eimeria Tenella Infection in Broiler Chickens, Jos - Nigeria
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Artificial Neural Network Model for Rainfall Data Analysis During 2004-2017 in Tamil Nadu, India – Prevailing Pattern Evaluation on Climate Change
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Clinical Evaluation of Significance of 25(Oh)D (Vitamin D) Status in Swine Flu (H1N1)
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Evaluation of Physicochemical Properties and Mineral Content of some Indigenous Spices Retailed in Ibadan, Nigeria
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Efficacy of Phytochemical Constituents of Castor Essential oil Towards the Mucor-Mycotic Mold Cunninghamella Bertholletiae
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Evaluation of Biological Activities of Opuntia Ficus Indica Cladodes Extract Against Cadmium-Induced Osteoporosis in Male Wistar Rats
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Lipid Assemblies as Tools for Drug Delivery
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Assessment of Self Medication Practice and Drugs Storage Among South Sudanese Community in Addis Ababa, Ethiopia
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A Critical Evaluation of the Estonian Cyber Incident
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Cephalometric Antero-Posterior Parameter Evaluation in Orthodontic Patients with Facial Asymmetries
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Process Evaluation of Auditable Pharmaceutical Transaction Service in Seka primary Hospital, Jimma Zone, South West Ethiopia
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Efficacy of Bat Guano on Growth and Yield of Some Hybrid Sunflower (Helianthus annus, L.) Cultivars in Sudan
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Evaluation of Gall Bladder Mucosal Changes in Relation to the Type of Stones in Patients Undergoing Laparoscopic Cholecystectomy: A Retrospective Study of 394 Patients
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Evaluation of Organic and Vermi Composts for Mass Culturing of Trichoderma Harzianum to be Used Against Soil-Borne Pathogen Sclerotium Rolfsii of Groundnut
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Overview of Imaging Modalities in Evaluation of Bone Allograft Viability
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Evaluation of Acacia- Guar Gum Combination as Delayed Release Coating Former on Solid Placebo Tablets
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Evaluation of Physicochemical, Spectral and Thermal Properties of Energy of Consciousness Healing Treated Iron Sulphate
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Evaluation of Anti-oxidation and Therapeutic Effect of Biofield Energy Healing Based Novel Test Formulation Using TNBS (Tri Nitro Benzene Sulfonic Acid) - Induced Ulcerative Colitis in Sprague Dawley Rats
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The Pharmacognostic Evaluation of Leaves of Medicinal Plants Tephrosia villosaand Cassia Tora (Linn.)
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Evaluation of Vitamin D3 metabolite (25-OH Vit D3), Neurotransmitter (ACh), and the Expression of Proinflammatory Cytokines (IL-6 and TNF-α) in Tissue Homogenate after Administration of Biofield Energy Healing-based Novel Proprietary Test Formulation and Biofield Treatment per se to the Animals in Vitamin D3 Deficiency Diet (VDD)-induced Sprague Dawley Rats
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Evaluation of the Isotopic Abundance Ratio of Consciousness Energy Healing Treated L-Tryptophan Using LC-MS Spectrometry
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Evaluation of Renal and Cardioprotective Potential of the Biofield Energy Treated Proprietary Test Formulation on L-NAME and High Fat Diet-Induced Cardiovascular Disorders in Sprague Dawley Rats
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The Efficacy of Some Plants Extracts on Fallarmyworm (Spodopterafrugiperda, J.E. Smizh) in Sudan
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Evaluation of Immunomodulatory Effect of a Novel Test Formulation in D-Galactose-Induced Aging Dysfunction in Sprague Dawley Rats
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Comparative Healing Efficacy of Platelet Rich Fibrin and Zinc Oxide Nanoparticles on Critical-Sized Ulnar Bone Defects in Rabbits
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Evaluation of Antioxidative Potential of the Biofield Energy Treated Proprietary Test Formulation on L-NAME and High Fat Diet-Induced Cardiovascular Disorders in Sprague Dawley Rats
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Evaluation of Cardiac Performance after Treatment with the Biofield Energy Treated Proprietary Test Formulation on L-NAME and High Fat Diet-Induced Cardiovascular Disorders in Sprague Dawley Rats
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Evaluation of Inflammatory Serum Cytokines after Treatment with the Consciousness Energy Healing Based Proprietary Test Formulation on Combination of Cecal Slurry, LPS and E. Coli Induced Systemic Inflammatory Response Syndrome (SIRS) in Sprague Dawley Rats
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Evaluation of Anthelmintic Activities of Fractions of Acanthus Montanus (Acanthaceae) on Adult Heligmosomoides Bakeri (Nematoda, Heligmosomatidae)
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Evaluation of Antioxidative Potential of the Biofield Energy Treated Proprietary Test Formulation on L-NAME and High Fat Diet-Induced Cardiovascular Disorders in Sprague Dawley Rats
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An Investigation of Emotional Intelligence and its Association with Self-Efficacy at Higher Education Level in Pakistan
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Antioxidant Activity of Pod Coat Extracts of Pigeon Pea (Cajanus Cajan L.) and Their Efficacy in Stabilization of Soybean Oil
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Developed and Field Performance Evaluation of a Combined Cultivator
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Functional State Hardware Evaluation System in Educational Medium
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The Evaluation of Forage Silage Related Traits Between Maize and Hybrid Giant Napier (Pennisetum Hydridum)
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Anti-COVID19 Vaccine among Workers at the Local Health Authority of Rieti (Italy). Study on the Vaccine Efficacy and Seroprevalence Post-Vaccination
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Evaluation of A Nutrition Feeding Algorithm for Children and Adolescents Undergoing Haematopoietic Stem Cell Transplantation (HSCT)
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Efficacy of Carumcarvi L. (Caraway), Eculaptuscamaldulensisdehnh (Red Gum) Andnigella Sativa (Black Seed) Against Greater Wax Mothgalleria Mellonellal.Innaeus (Lepidoptera:Pyralidae)
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Comparison the Diagnostic Value of Doppler Ultrasonography to Biopsy, in Evaluation of Post-transplant Complications and Kidney Function
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Evaluation of Cinnamon Supplementation on Insulin Resistance, BMI and Estradiol Levels in Women with Polycystic Ovary Syndrome: A Double-Blinded Randomized Controlled Clinical Trial
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A Pressure Sensitive Occlusal Contact Indicator for Implant Restorations: An Observational Clinical Evaluation
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A Review on Drug Design by the Application of Computer
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Evaluation of selection indices for heat tolerance and their correlation with yield in some chickpea (Cicer Arietinum L.) genotypes of sudan
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Risk Management: Emerging critical issues during the hospital administration of drug therapy
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Evaluation and Comparision of Total Phenolics, Total Flavonoids and Antioxidant Activity of A. Mexicana Aerial Parts in Different Solvents
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Evaluation of Growth and some Growth Analysis Components in Sugar beet Genotypes Grown under Low Nitrogen Fertilizer Levels in Khartoum State- Sudan
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Self-Efficacy and Smoking Cessation: A Mixed Method Study among Adult Smokers in Fiji
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A case of delayed allergy after cyanoacrylate closure of varicose veins, diagnosed by drug-induced lymphocyte stimulation test
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Evaluation Of Physicochemical Separation Characteristics of Pig Manure According to the Type of Solid-Liquid Separator Processes
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Human Immunodeficiency Virus Drug Resistance (HIVDR) and Baseline Characteristics among Antiretroviral Therapy (ART) experienced Children and Adolescents under the care of Chidamoyo Christian Hospital in Hurungwe, Zimbabwe
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Stereoselective Synthesis of N-Glycosyl Oxazolines and Evaluation of Their Antiproliferative Activity
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Spirometric profile of people living with HIV on antiretroviral drugs in Abidjan
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Evaluation of Non Isolated DC-DC Boost Converter for Interfacing Solar Pv Panel
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Measuring Quality Change in the Market for Anti-Ulcer Drugs
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A 12-week, Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial Evaluating the Efficacy and Safety of DKB-131 in Knee Arthritis
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Osteoarthritis in Older Adults: Is More Emphasis on Managing and Mitigating its Stressful Ramifications, and Enhancing Coping, and Self Efficacy Cognitions Indicated?
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Call to Action: The Need for Adverse Drug Event (ADE) Standardization and Codification Through Improved ADE Definitions, Documentation and Mapping, as well as More Refined Medication Definitions
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Efficacy and Safety of Pulsed Magnetic Therapy in Sleep related Disorders: A Remote, Randomized, Double-Blind, Placebo-Controlled Trial
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Review on Frequency Neurofeedback on Autism Spectrum Disorder: Overview, Efficacy and Research Direction
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Retraction: Efficacy of BCG Vaccine and Role of Non Specific Sensitivity Due to Atypical Mycobacteria
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Efficacy and Safety of Lercanidipine Combination in Hypertensive Patients
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Efficacy of Neemraj and Beauvitech on Abundance and Distribution of Arthropod Pests in Soil and Hydroponically Grown Strawberry
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Retrospective Evaluation of Well Differentiated Thyroid Cancer Treatment Outcomes: 50 year experience at the University of Puerto Rico
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Toxicology and Drug Safety Issues: A Review Article
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Evaluation of Combined Ultrasonography and Cone Beam Computed Tomography for Clinical Imaging: A Negative Results Study
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Characterization of People Receiving 2-Drug Regimens (2DR) for HIV Management in Italy
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Histologic and Histomorphometric Evaluation of Implant Osseointegration of a Dental Implant Three Years in Function Removed Due to Abutment Fracture
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