Research Topic · Peer-Reviewed

Clinical Cancer Trials

Clinical cancer trials are prospective research studies that evaluate new approaches to the prevention, detection, diagnosis, and treatment of cancer in human participants. They form the essential bridge between laboratory discovery and clinical practice, testing whether candidate drugs, biologics, devices, or strat…

Curated from this journal's research 📚 9 peer-reviewed articles cited Cited 15× across the literature 🔖 ISSN 2328-0182 🗓 Reviewed June 2026

Overview

Clinical cancer trials are prospective research studies that evaluate new approaches to the prevention, detection, diagnosis, and treatment of cancer in human participants. They form the essential bridge between laboratory discovery and clinical practice, testing whether candidate drugs, biologics, devices, or strategies are safe and effective before they enter routine use. Therapeutic trials are conventionally organized into phases: early-phase studies assess safety, tolerability, and dosing in small groups; intermediate phases evaluate efficacy and further define safety; and large comparative phases test the new intervention against the current standard of care, often through randomization. Beyond treatment, clinical cancer trials also address prevention, screening, diagnostics, and supportive and quality-of-life endpoints. Their scientific validity depends on clearly defined objectives, appropriate participant selection, control of bias through randomization and blinding where feasible, predefined outcome measures, and rigorous statistical analysis, all conducted under ethical oversight and informed consent. Trials increasingly incorporate molecular biomarkers and targeted and immunological agents, matching therapies to tumor characteristics and supporting biomarker-driven and personalized approaches. The interpretation of results requires attention to endpoints, generalizability, and the balance of benefit and harm. As the principal means of generating reliable evidence in oncology, clinical cancer trials underpin advances in cancer care and the responsible introduction of new diagnostics and therapies into practice.

Research published in this journal

9 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 9 articles above have been cited 15 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Clinical Cancer Trials, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Advanced Pharmaceutical Science And Technology (ISSN 2328-0182).

Journal editorial board
natalia malara · Italy Saba Khalilpour · Italy Haseeb Khan · United States

This page summarises published research for orientation; it is not medical or professional advice.