Department of Pharmacy,
University of Georgia
HM-1200 Georgia Regents University Campus
1120 15th Street
Augusta, GA 30912,United States
- My research interests focus on the molecular events underlying neurological diseases.
- In my studies I concentrate on three diseases: Parkinson, Alzheimer and Cerebral stroke.
- The long-term goal to identify potential new drug targets for the development of causative treatments.
- These are progressive diseases of the nervous system involving damage or loss of neurons in the brain.
- The causes of the diseases are unknown but recent evidence suggests a multifactorial origin involving genetic and environmental factors.
- Considerable efforts have been made to determine the cellular mechanisms that might underlie the cell death in these diseases.
- Over the years, several pathogenic hypotheses have been proposed, including oxidative stress, apoptosis, excitotoxicity, inflammation and mitochondrial dysfunction.
- However, up to now it is not known which of these metabolic pathways participate in the process of cell death, if and how they interact and which genes are regulating this complex network.
- Dr. Ishrat working as a Research scientist at University of Georgia, Augusta, GA.
- My research revolves around the importance of vascular protection in the acute stroke period to improve outcome of ischemic stroke.
- Also, I am trying to identify tactics for decreasing vascular damage after ischemic stroke in an attempt to develop new therapies for stroke patients.