Mice
llar Electrokinetic Chromatography Micellar Electrokinetic Chromatography (MECC) is a sophisticated analytical technique used to separate and analyse chemical compounds in a sample. It is based on the interaction of an electrically charged surfactant (e.g. an ionic surfactant such as sodium dodecyl sulfate) and an electric field applied in a capillary tube. As the sample runs through the capillary, the surfactant micelles migrate according to their charge and size, resulting in the separation of the compounds in the sample. MECC is a very powerful and reliable technique to achieve separations with high resolution and low sample consumption. It has been successfully used in various analytical and preparative applications such as the determination of drugs in biological fluids, the determination of impurities in pharmaceuticals, and the isolation of biomolecules. Furthermore, due to its low cost, ease of operation, and short analysis time, MECC is becoming a popular alternative to other conventional chromatographic techniques.
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