Sperm DNA Fragmentation

Sperm DNA fragmentation is the degree of chromosomal damage in sperm cells, usually measured through sperm chromatin structure assay (SCSA). High levels of sperm DNA fragmentation can lead to reduced fertility in males and increase the risk of having a miscarriage or a child with genetic disorders. Sperm DNA fragmentation can be caused by many factors, such as environmental pollutants, smoking, alcohol consumption, and prescription medications. Recent research suggests that lifestyle modifications, like exercise and reducing stress, can reduce sperm DNA fragmentation. Certain treatments, such as assisted reproductive techniques, can also be used to improve fertility when sperm DNA fragmentation is present.