Inhibition

of ribonucleotide reductase Inhibition of ribonucleotide reductase (RNR) is a type of drug therapy used to treat some cancers. RNR is an enzyme involved in DNA synthesis, and its inhibition prevents the body from creating new DNA, leading to death of cancer cells. RNR inhibitors are important anti-cancer drugs that are commonly used in combination with other therapies to treat a variety of cancers, including breast, ovarian, and non-small cell lung cancer. By inhibiting this enzyme, the cancer cells are unable to replicate and spread, thus leading to the death of the cancer cells, while allowing other healthy cells to remain unharmed. RNR inhibition also plays a role in preventing cancer cells from developing resistance to other treatments, making it an important part of an effective cancer treatment plan.