Resistance to Thyroid Hormone

Resistance to thyroid hormone (RTH) is a rare inherited disorder, caused by a genetic mutation, in which the body does not respond to thyroid hormone normally. This results in increased production of thyroid hormones, resulting in hyperthyroidism. Treatment for RTH includes lifelong hormone replacement therapy. Early diagnosis and treatment is key to preventing long-term complications such as heart disease, osteoporosis, infertility, and premature death. RTH can also lead to intellectual disabilities and delayed growth and development in children. RTH is a serious condition that requires careful management. Recognizing the symptoms, seeking appropriate medical advice, and receiving timely treatment are essential for preventing long-term health complications. Early diagnosis and treatment of RTH can help improve a patient’s quality of life and help them live a normal life.