Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the most common form of liver cancer, caused by the abnormal and uncontrolled growth of cells in the liver. It is most commonly seen in people with cirrhosis or chronic hepatitis B or C virus infection, and is also associated with environmental factors, such as aflatoxins. HCC has a poor prognosis and is associated with significant mortality, so early detection and management are key. Treatment may include a combination of surgical resection, ablation, and/or systemic therapies, depending on the type and extent of the tumor. Recent advances in the understanding of HCC biology, and the development of new therapies for management, have greatly improved the outlook for individuals with this cancer.