Research Topic · Peer-Reviewed

Alcoholic Liver Disease

Alcoholic liver disease (ALD) is a spectrum of hepatic injury caused by chronic excessive alcohol consumption, ranging from reversible fatty liver (steatosis) through alcoholic hepatitis to progressive fibrosis and cirrhosis. The pathophysiology involves the hepatic metabolism of ethanol generating reactive and toxi…

Curated from this journal's research 📚 10 peer-reviewed articles cited Cited 33× across the literature 🔖 ISSN 2578-2371 🗓 Reviewed June 2026

Overview

Alcoholic liver disease (ALD) is a spectrum of hepatic injury caused by chronic excessive alcohol consumption, ranging from reversible fatty liver (steatosis) through alcoholic hepatitis to progressive fibrosis and cirrhosis. The pathophysiology involves the hepatic metabolism of ethanol generating reactive and toxic intermediates, oxidative stress, inflammation, and altered lipid handling, which together drive hepatocyte damage and scarring; advanced disease may culminate in liver failure and hepatocellular carcinoma. ALD is among the leading preventable causes of chronic liver disease worldwide and frequently coexists with nutritional and metabolic disturbances. Research relevant to this topic includes hospital-based retrospective studies characterising the magnitude and trends of chronic and alcohol-related liver disease, the evaluation of vitamin D deficiency in patients with chronic liver disease, and the relationship between plasma biomarkers, alcohol consumption, liver enzymes, and genetic polymorphism in alcohol-use disorder. Studies of liver stiffness in relation to portal hypertension and decompensation, and of nutritional and epigenetic influences on the liver, situate ALD within broader hepatology. Sub-areas include alcohol metabolism and hepatotoxicity, steatosis and steatohepatitis, fibrosis and cirrhosis, nutritional management, and biomarkers for staging and risk. Understanding ALD is central to the prevention, diagnosis, and management of alcohol-related liver injury and its systemic complications.

Research published in this journal

10 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2015

Epigenetics and Nutrition

Exact topic International Journal of Nutrition Cited by 2 doi:10.14302/issn.2379-7835.ijn-14-603

How this research is being cited

The 10 articles above have been cited 33 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Alcoholic Liver Disease, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Spleen And Liver Research (ISSN 2578-2371).

Journal editorial board
Florin Graur · Romania

This page summarises published research for orientation; it is not medical or professional advice.