Myasthenia Gravis

Myasthenia gravis is a chronic autoimmune neuromuscular disorder characterized by weakness and rapid fatigue of voluntary muscles. It occurs when the immune system mistakenly attacks the nicotinic acetylcholine receptors of muscle fibers, which prevents the release of acetylcholine, a neurotransmitter needed to activate muscles. Myasthenia gravis affects up to 20 in every 100,000 people worldwide, and is more visible in females. Although the cause of myasthenia gravis is unknown, treatments such as medications, surgery, and plasmapheresis are available to help improve and manage the symptoms, including muscle weakness, blurry vision, and difficulty speaking, eating, and breathing. These treatments have been effective in improving the quality of life for many people with myasthenia gravis.